ArticleInternational journal of rheumatology2010
Renal manifestations in scleroderma: evidence for subclinical renal disease as a marker of vasculopathy.
Article in International journal of rheumatology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 66 citations in OpenAlex.
- Bibliometric insights into systemic sclerosis with renal involvement: trends, contributions, and future directions.Renal failure · 2025Article
- Renal Vascular Affection in Systemic Sclerosis Patients and Possible Correlation with Peripheral Vascular Involvement Assessed by Nailfold Capillaroscopy.Mediterranean journal of rheumatology · 2025Article
- Cardio-Rheumatology Insights Into Hypertension: Intersection of Inflammation, Arteries, and Heart.American journal of hypertension · 2024Review
- Iloprost infusion reduces serological cytokines and hormones of hypoxia and inflammation in systemic sclerosis patients.Clinical and experimental medicine · 2024Article
- Nephrotic syndrome due to focal segmental glomerulosclerosis complicating scleroderma: a case report.Journal of medical case reports · 2024Article
- A new immune disease: systemic hypertension.Clinical kidney journal · 2023Review
- Evaluation of renal damage in a bleomycin-induced murine model of systemic sclerosis.Iranian journal of basic medical sciences · 2023Article
- Kidney Involvement in Systemic Sclerosis.Journal of personalized medicine · 2022Review
- Systemic Scleroderma-Definition, Clinical Picture and Laboratory Diagnostics.Journal of clinical medicine · 2022Review
- Journey of a patient with scleroderma from renal failure up to kidney transplantation.World journal of transplantation · 2021Review
- Autoimmune-mediated renal disease and hypertension.Clinical science (London, England : 1979) · 2021Review
- Systemic sclerosis and end-stage renal disease: study of patient characteristics, follow-up and outcomes in France.Journal of nephrology · 2021Article
- Soluble Biomarkers for Prediction of Vascular and Gastrointestinal Disease Severity in Patients with Systemic Sclerosis.Current treatment options in rheumatology · 2021Article
- Diagnosing renal involvement in connective tissue disease: interpretation of anti-nuclear autoantibody tests.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020Article
- Scientific study on acid rain and subsequent pH-imbalances in humans, case studies, treatments.European journal of clinical nutrition · 2020Article
- Systemic sclerosis medications and risk of scleroderma renal crisis.BMC nephrology · 2019Article
- Mechanisms of hypertension in autoimmune rheumatic diseases.British journal of pharmacology · 2019Review
- Autoimmune Disease-Associated Hypertension.Current hypertension reports · 2019Review
- Kidney involvement in systemic sclerosis: From pathogenesis to treatment.Journal of scleroderma and related disorders · 2018Review
- Clinical pattern of systemic sclerosis in Central Ukraine. Association between clinical manifestations of systemic sclerosis and hypertension.Reumatologia · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Scleroderma is a disease characterized by immune activation, vasculopathy, fibroblast stimulation, and connective tissue fibrosis. End-organ damage occurs due to progressive tissue fibrosis and vasculopathy. Markers of incipient vasculopathy have not been well studied in scleroderma. However, reduced renal functional reserve and proteinuria are common indicators of progressive vasculopathy in diabetic and hypertensive vasculopathy. Recent studies suggest a strong association between renal involvement and outcomes in scleroderma, with a threefold increased risk of mortality from pulmonary hypertension if renal insufficiency is present. We review the types of renal involvement seen in scleroderma and the data to support the use of renal parameters including proteinuria, glomerular filtration rate, and renal vascular dynamics measured with Doppler ultrasound to identify subclinical renal insufficiency. Further studies are warranted to investigate the use of renal parameters as prognostic indicators in scleroderma.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.