ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2010
White matter fiber degradation attenuates hemispheric asymmetry when integrating visuomotor information.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Substance use disorder and altered hemispheric asymmetries: A systematic review.Clinical psychology review · 2025Pooled it
- Visuoperceptive Impairments in Severe Alcohol Use Disorder: A Critical Review of Behavioral Studies.Neuropsychology review · 2021Review
- Asymmetry in the Central Nervous System: A Clinical Neuroscience Perspective.Frontiers in systems neuroscience · 2021Review
- Structural remodeling secondary to functional remodeling in advanced-stage peripheral facial neuritis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Article
- Quantitative Digitography Measures Fine Motor Disturbances in Chronically Treated HIV Similar to Parkinson's Disease.Frontiers in aging neuroscience · 2020Article
- Alterations in the Structural and Functional Connectivity of the Visuomotor Network of Children With Periventricular Leukomalacia.Seminars in pediatric neurology · 2019Article
- Quantitative Analysis of Kynurenine Aminotransferase II in the Adult Rat Brain Reveals High Expression in Proliferative Zones and Corpus Callosum.Neuroscience · 2018Article
- Ethanol-Induced TLR4/NLRP3 Neuroinflammatory Response in Microglial Cells Promotes Leukocyte Infiltration Across the BBB.Neurochemical research · 2016Article
- The Resting Brain of Alcoholics.Cerebral cortex (New York, N.Y. : 1991) · 2015Article
- Cross-hemispheric collaboration and segregation associated with task difficulty as revealed by structural and functional connectivity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Human alcohol-related neuropathology.Acta neuropathologica · 2014Review
- Fiber tract-driven topographical mapping (FTTM) reveals microstructural relevance for interhemispheric visuomotor function in the aging brain.NeuroImage · 2013Article
- Inferior frontal white matter asymmetry correlates with executive control of attention.Human brain mapping · 2013Article
- Visual search and the aging brain: discerning the effects of age-related brain volume shrinkage on alertness, feature binding, and attentional control.Neuropsychology · 2013Article
- How acute and chronic alcohol consumption affects brain networks: insights from multimodal neuroimaging.Alcoholism, clinical and experimental research · 2012Review
- White matter fiber compromise contributes differentially to attention and emotion processing impairment in alcoholism, HIV-infection, and their comorbidity.Neuropsychologia · 2012Article
- The diffusion tensor imaging toolbox.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Along-tract statistics allow for enhanced tractography analysis.NeuroImage · 2012Article
- Synchrony of corticostriatal-midbrain activation enables normal inhibitory control and conflict processing in recovering alcoholic men.Biological psychiatry · 2012Article
- Hemispheric asymmetries: the comparative view.Frontiers in psychology · 2012Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Degradation of white matter fibers can affect the transmission of signals in brain circuits that normally enable integration of highly lateralized visual and motor processes. Here, we used diffusion tensor imaging tractography in combination with functional magnetic resonance imaging to examine the specific contributions of interhemispheric and intrahemispheric white matter fibers to functional measures of hemispheric transfer and parallel information processing using bilateral and unilateral left and right visual field stimulation in normal and compromised systems. In healthy adults, a greater degree of bilateral processing advantage with the left (nondominant) hand correlated with higher integrity of callosal fibers connecting occipital cortices, whereas less unilateral processing advantage with the right hand correlated with higher integrity of left-hemispheric posterior cingulate fibers. In contrast, alcoholics who have compromised callosal integrity showed less bilateral processing advantage than controls when responding with the left hand and greater unilateral processing advantage when responding with the right hand. We also found degraded left posterior cingulate and posterior callosal fibers in chronic alcoholics, which is consistent with functional imaging results of less left posterior cingulate and extrastriate cortex activation in alcoholics than controls when processing bilateral compared with unilateral visual field stimulation. Together, our results demonstrated that interhemispheric and intrahemispheric white matter fiber pathways mediate visuomotor integration asymmetrically and that subtle white matter fiber degradation in alcoholism attenuated the normal pattern of hemispheric asymmetry, which may have ramifications for the efficiency of visual information processing and fast response execution.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.