Evidence map›Paper›PMID 20826228›Full record

ReviewComparative biochemistry and physiology. Toxicology & pharmacology : CBP2011

Marine pharmacology in 2007-8: Marine compounds with antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, antituberculosis, and antiviral activities; affecting the immune and nervous system, and other miscellaneous mechanisms of action.

Alejandro M S Mayer, Abimael D Rodríguez, Roberto G S Berlinck, Nobuhiro Fusetani

Open access · greenAbstract readReview
In one paragraph

Review in Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 1 pooled it
23.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 1 synthesis or guideline pooled it, 266 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Cultivation ofLife (Basel, Switzerland) · 2024
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  9. Article
  10. Article
  11. Total Synthesis of (±)-Tetrahedron letters · 2023
    Article
  12. Review
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  17. Comparison of volatile chemical components ofTurkish journal of chemistry · 2022
    Article
  18. Article
  19. Article
  20. Review

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 4 countries.

Alejandro M S MayerDepartment of Pharmacology, Chicago College of Osteopathic Medicine, Midwestern University, 555 31st Street, Downers Grove, IL 60515, USA. amayer@midwestern.edu
Abimael D Rodríguez
Roberto G S Berlinck
Nobuhiro Fusetani
Hokkaido University · JPMidwestern University · USUniversidade Federal de São Carlos · BRUniversity of Puerto Rico System · PR

Funding

New Leads Against Cancer and Infectious Diseases from Puerto Rican Reef SpeciesSC1GM086271 · NIGMS · UNIVERSITY OF PUERTO RICO RIO PIEDRAS · PI RODRIGUEZ, ABIMAEL D · 2010 to 2013
$1.2M
NIGMS NIH HHS 1SC1GM086271-01A1NIGMS NIH HHS SC1 GM086271
6 · The paper itself

Abstract

The peer-reviewed marine pharmacology literature in 2007-8 is covered in this review, which follows a similar format to the previous 1998-2006 reviews of this series. The preclinical pharmacology of structurally characterized marine compounds isolated from marine animals, algae, fungi and bacteria is discussed in a comprehensive manner. Antibacterial, anticoagulant, antifungal, antimalarial, antiprotozoal, antituberculosis and antiviral activities were reported for 74 marine natural products. Additionally, 59 marine compounds were reported to affect the cardiovascular, immune and nervous systems as well as to possess anti-inflammatory effects. Finally, 65 marine metabolites were shown to bind to a variety of receptors and miscellaneous molecular targets, and thus upon further completion of mechanism of action studies, will contribute to several pharmacological classes. Marine pharmacology research during 2007-8 remained a global enterprise, with researchers from 26 countries, and the United States, contributing to the preclinical pharmacology of 197 marine compounds which are part of the preclinical marine pharmaceuticals pipeline. Sustained preclinical research with marine natural products demonstrating novel pharmacological activities, will probably result in the expansion of the current marine pharmaceutical clinical pipeline, which currently consists of 13 marine natural products, analogs or derivatives targeting a limited number of disease categories.

Indexed as

Marine BiologyAnimalsAnti-Bacterial AgentsAnticoagulantsAntifungal AgentsAnti-Inflammatory AgentsAntimalarialsAntiprotozoal AgentsAntitubercular AgentsAntiviral AgentsBiological ProductsCardiovascular SystemFungiHumansNervous SystemPharmaceutical PreparationsAnti-Bacterial AgentsAnticoagulantsAntifungal AgentsAnti-Inflammatory AgentsAntimalarialsAntiprotozoal AgentsAntitubercular AgentsAntiviral AgentsBiological ProductsPharmaceutical Preparations

Identifiers

PMID20826228
PMCPMC7110230
OpenAlexW2569373158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.