Evidence map›Paper›PMID 20826220›Full record

ArticleAnaerobe2010

Genetic analysis of mobile tetQ elements in oral Prevotella species.

Gena D Tribble, John J Garza, Victor L Yeung, Todd W Rigney, Doan-Hieu V Dao, Paulo H Rodrigues, Clay B Walker, Charles J Smith

Open access · greenAbstract read
In one paragraph

Article in Anaerobe, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Bridging the gap:Gut microbes · 2026
    Review
  2. The redefined identity ofJournal of bacteriology · 2026
    Review
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  11. Bacterial sex in dental plaque.Journal of oral microbiology · 2013
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Gena D TribbleDepartment of Periodontics, University of Texas Health Science Center at Houston, 77030, USA. gena.d.tribble@uth.tmc.edu
John J Garza
Victor L Yeung
Todd W Rigney
Doan-Hieu V Dao
Paulo H Rodrigues
Clay B Walker
Charles J Smith
The University of Texas Health Science Center at Houston · USUniversity of Florida · USEast Carolina University · USThe University of Texas Health Science Center · US

Funding

Porphyromonas gingivalis Horizontal DNA Transfer and Genetic VariationR01DE019634 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TRIBBLE, GENA D · 2010 to 2013
$1.3M
Antibiotic Resistance Transfer in Oral AnaerobesR03DE016562 · NIDCR · UNIVERSITY OF FLORIDA · PI LAMONT, RICHARD J · 2005 to 2006
$144k
NIDCR NIH HHS DE016562NIDCR NIH HHS R01 DE019634NIDCR NIH HHS R03 DE016562
6 · The paper itself

Abstract

Prevotella species are members of the bacterial oral flora and are opportunistic pathogens in polymicrobial infections of soft tissues. Antibiotic resistance to tetracyclines is common in these bacteria, and the gene encoding this resistance has been previously identified as tetQ. The tetQ gene is also found on conjugative transposons in the intestinal Bacteroides species; whether these related bacteria have transmitted tetQ to Prevotella is unknown. In this study, we describe our genetic analysis of mobile tetQ elements in oral Prevotella species. Our results indicate that the mobile elements encoding tetQ in oral species are distinct from those found in the Bacteroides. The intestinal bacteria may act as a reservoir for the tetQ gene, but Prevotella has incorporated this gene into an IS21-family transposon. This transposon is present in Prevotella species from more than one geographical location, implying that the mechanism of tetQ spread between oral Prevotella species is highly conserved.

Indexed as

Genes, BacterialInterspersed Repetitive SequencesTetracycline ResistanceBacteroidesConjugation, GeneticHumansMouthPrevotellaSequence Analysis, DNA

Identifiers

PMID20826220
PMCPMC3010312
OpenAlexW1977223904

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.