ReviewPhilosophy, ethics, and humanities in medicine : PEHM2010
Is the use of sentient animals in basic research justifiable?
Review in Philosophy, ethics, and humanities in medicine : PEHM, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Critical evaluation of challenges and future use of animals in experimentation for biomedical research.International journal of immunopathology and pharmacology · 2016Pooled it
- Developing more inclusive approaches to animal research and patient involvement.Medicine, health care, and philosophy · 2025Article
- Burning down the house: reinventing drug discovery in psychiatry for the development of targeted therapies.Molecular psychiatry · 2023Review
- Modeling the Tumor Microenvironment and Pathogenic Signaling in Bone Sarcoma.Tissue engineering. Part B, Reviews · 2020Review
- Harm-Benefit Analysis May Not Be the Best Approach to Ensure Minimal Harms and Maximal Benefits of Animal Research-Alternatives Should Be Explored.Animals : an open access journal from MDPI · 2020Article
- Joining forces: the need to combine science and ethics to address problems of validity and translation in neuropsychiatry research using animal models.Philosophy, ethics, and humanities in medicine : PEHM · 2020Article
- The Three Rs of Animal Research: What they Mean for the Institutional Animal Care and Use Committee and Why.Science and engineering ethics · 2016Article
- The flaws and human harms of animal experimentation.Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees · 2015Article
- Letter to the editor.Theoretical medicine and bioethics · 2014Article
- A review of the Institute of Medicine's analysis of using chimpanzees in biomedical research.Science and engineering ethics · 2014Article
- Systematic reviews of animal models: methodology versus epistemology.International journal of medical sciences · 2013Review
- Animal models and conserved processes.Theoretical biology & medical modelling · 2012Article
- The Nuremberg Code subverts human health and safety by requiring animal modeling.BMC medical ethics · 2012Review
- The institutional review board is an impediment to human research: the result is more animal-based research.Philosophy, ethics, and humanities in medicine : PEHM · 2011Article
- Respice...prospice: philosophy, ethics and medical care- past, present, and future.Philosophy, ethics, and humanities in medicine : PEHM · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animals can be used in many ways in science and scientific research. Given that society values sentient animals and that basic research is not goal oriented, the question is raised: "Is the use of sentient animals in basic research justifiable?" We explore this in the context of funding issues, outcomes from basic research, and the position of society as a whole on using sentient animals in research that is not goal oriented. We conclude that the use of sentient animals in basic research cannot be justified in light of society's priorities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.