ArticleEnvironmental microbiology2011
Virulence of an emerging pathogenic lineage of Vibrio nigripulchritudo is dependent on two plasmids.
Article in Environmental microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 31 citations in OpenAlex.
- The ecology and evolution of microbial immune systems: a look on the wild vibrio side.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Cell cycle-coordinated maintenance of theEcoSal Plus · 2023Review
- Molecular Targets for Coevolutionary Interactions Between Pacific Oyster Larvae and Their SympatricFrontiers in microbiology · 2019Article
- Ancestral gene acquisition as the key to virulence potential in environmental Vibrio populations.The ISME journal · 2018Article
- Coordinated delivery and function of bacterial MARTX toxin effectors.Molecular microbiology · 2018Review
- Differential regulation of actin-activated nucleotidyl cyclase virulence factors by filamentous and globular actin.PloS one · 2018Article
- Article
- Nigritoxin is a bacterial toxin for crustaceans and insects.Nature communications · 2017Article
- The opportunistic marine pathogen Vibrio parahaemolyticus becomes virulent by acquiring a plasmid that expresses a deadly toxin.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Multifunctional-autoprocessing repeats-in-toxin (MARTX) Toxins of Vibrios.Microbiology spectrum · 2015Review
- Genomic diversification in strains of Rickettsia felis Isolated from different arthropods.Genome biology and evolution · 2014Article
- Vibrio vulnificus biotype 3 multifunctional autoprocessing RTX toxin is an adenylate cyclase toxin essential for virulence in mice.Infection and immunity · 2014Article
- Comparative genomics of pathogenic lineages of Vibrio nigripulchritudo identifies virulence-associated traits.The ISME journal · 2013Article
- Article
- Identification of a His-Asp-Cys catalytic triad essential for function of the Rho inactivation domain (RID) of Vibrio cholerae MARTX toxin.The Journal of biological chemistry · 2013Article
- Implication of lateral genetic transfer in the emergence of Aeromonas hydrophila isolates of epidemic outbreaks in channel catfish.PloS one · 2013Article
- Pathotyping of Vibrio isolates by multiplex PCR reveals a risk of virulent strain spreading in New Caledonian shrimp farms.Microbial ecology · 2012Article
- The Photobacterium damselae subsp. damselae hemolysins damselysin and HlyA are encoded within a new virulence plasmid.Infection and immunity · 2011Article
- Article
- Conserved small RNAs govern replication and incompatibility of a diverse new plasmid family from marine bacteria.Nucleic acids research · 2011Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
Vibrioses are the predominant bacterial infections in marine shrimp farms. Vibrio nigripulchritudo is an emerging pathogen of the cultured shrimp Litopenaeus stylirostris in New Caledonia and other regions in the Indo-Pacific. The molecular determinants of V. nigripulchritudo pathogenicity are unknown; however, molecular epidemiological studies have revealed that recent pathogenic V. nigripulchritudo isolates from New Caledonia all cluster into a monophyletic clade and contain a small plasmid, pB1067. Here, we report that a large plasmid, pA1066 (247 kb), can also serve as a marker for virulent V. nigripulchritudo, and that an ancestral version of this plasmid was likely acquired prior to other virulence-linked markers. Additionally, we demonstrate that pA1066 is critical for the full virulence of V. nigripulchritudo in several newly developed experimental models of infection. Plasmid pB1067 also contributes to virulence; only strains containing both plasmids induced the highest level of shrimp mortality. Thus, it appears that these plasmids, which are absent from non-pathogenic isolates, may be driving forces, as well as markers, for the emergence of a pathogenic lineage of V. nigripulchritudo.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.