ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2010
Patient and peri-operative predictors of morbidity and mortality after esophagectomy: American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP), 2005-2008.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.
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Who cites it
64 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Venous thromboembolism after esophagectomy for cancer: a systematic review of the literature to evaluate incidence, risk factors, and prophylaxis.Surgery today · 2022Pooled it
- Effect of Perioperative Palliative Care on Health-Related Quality of Life Among Patients Undergoing Surgery for Cancer: A Randomized Clinical Trial.JAMA network open · 2023Trial
- Endoscopic mucosal ischemic index for predicting anastomotic complications after esophagectomy: a prospective cohort study.Langenbeck's archives of surgery · 2023Trial
- A Multicenter, Randomized Controlled Trial of Perioperative Palliative Care Surrounding Cancer Surgery for Patients and Their Family Members (PERIOP-PC).Journal of palliative medicine · 2019Trial
- A nomogram predicting the risk of postoperative pneumonia after esophagectomy in esophageal carcinoma.Frontiers in medicine · 2025Article
- APACHE II, SOFA, and SAPS III after transhiatal and thoracoscopic in prone position esophagectomy for esophageal cancer: a single-center retrospective cohort analysis.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2025Article
- Essential updates 2022/2023: Recent advances in perioperative management of esophagectomy to improve operative outcomes.Annals of gastroenterological surgery · 2024Review
- Article
- Association of DLT versus SLT with postoperative pneumonia during esophagectomy in China: a retrospective comparison study.BMC anesthesiology · 2023Article
- Postoperative complications after esophagectomy for cancer, neoadjuvant chemoradiotherapy compared to neoadjuvant chemotherapy: A single institutional cohort study.Clinical and translational radiation oncology · 2023Article
- Acute clinical and financial outcomes of esophagectomy at safety-net hospitals in the United States.PloS one · 2023Article
- Short-term outcome for high-risk patients after esophagectomy.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2022Article
- Trajectories of Patient-Reported Outcomes After Palliative Gastrointestinal Surgery in Advanced Cancer: Is Good Quality of Life Sustainable?Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2022Article
- Association between psychological distress of each points of the treatment of esophageal cancer and stress coping strategy.BMC psychology · 2022Article
- Preoperative bacterial culture can predict severe pneumonia in patients receiving esophagectomy.Fukushima journal of medical science · 2022Article
- Tackling Surgical Morbidity and Mortality through Modifiable Risk Factors in Cancer Patients.Nutrients · 2022Review
- Minimally invasive esophagectomy may contribute to low incidence of postoperative surgical site infection in patients with poor glycemic control.Langenbeck's archives of surgery · 2022Article
- Chronological Changes in Skeletal Muscle Mass Two Years after Minimally Invasive Esophagectomy: A Prospective Cohort Study.Surgical endoscopy · 2022Article
- Socioeconomic factors in timing of esophagectomy and association with outcomes.Journal of surgical oncology · 2021Article
- A nomogram for predicting postoperative pulmonary infection in esophageal cancer patients.BMC pulmonary medicine · 2021Article
4 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeOur aim was to determine what specific patient and peri-operative factors contribute to major complications after esophagectomy.
methodsUsing the American College of Surgeons National Surgical Quality Improvement Program database, data for esophagectomies between the years 2005 and 2008 were extracted and analyzed. Thirty-day post-operative complications were classified into seven major groups: (1) wound infections, (2) respiratory complications (pneumonia, intubation), (3) cardiac complications, (4) deep venous thrombosis, (5) sepsis/septic shock, (6) re-operation, and (7) death. Univariate analysis and logistic regression modeling were performed to determine if a significant association existed between patient factors or peri-operative factors and these post-operative complications.
resultsOne thousand thirty-two patients who underwent esophagectomy were identified. Diabetes was the strongest pre-operative independent predictor of death (odds ratio (OR) 10.98; 95% confidence interval (CI) 1.37-1.15, p < 0.1) or respiratory (OR 1.86; 95% CI 1.03-3.29, p = 0.04) or cardiac (OR 5.14; 95% CI 1.93-13.20, p < 0.01) complications following esophagectomy. Thoracotomy performed during the operation was not associated with an increased risk of respiratory or cardiac complications.
conclusionsThe major predictors of morbidity after an esophagectomy are the patient factors of diabetes, dyspnea, peripheral vascular disease, and cerebrovascular accident while the peri-operative factors are pre-operative international normalized ratio, contaminated wound classification, and American Society of Anesthesiologists class. Similarly, the major predictors of mortality are diabetes, dyspnea, and age for patient factors and contaminated wound classification for peri-operative factors.
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