ArticlePLoS biology2010
Precise temperature compensation of phase in a rhythmic motor pattern.
Article in PLoS biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers.
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Who cites it
96 citing papers in PubMed.
- Similarities betweeneNeuro · 2026Article
- Compensation of the effects of temperature on a motor system in the crab,bioRxiv : the preprint server for biology · 2026Article
- Temperature and pH-dependent potassium currents of muscles of the stomatogastric nervous system of the crab,iScience · 2026Article
- The combined effects of temperature and salinity on the stomatogastric nervous system of two species of decapod crustacea.Journal of neurophysiology · 2026Article
- Temperature robustness of the timing network within songbird premotor nucleus HVC.Journal of computational neuroscience · 2026Article
- Temperature and pH-dependent Potassium Currents of Muscles of the Stomatogastric Nervous System of the Crab,bioRxiv : the preprint server for biology · 2025Article
- The dorsal/ventral subdivision of the hindbrain predates the tunicate/vertebrate split.bioRxiv : the preprint server for biology · 2025Article
- Homeostatic regulation of a motor circuit through temperature sensing rather than activity sensing.Current biology : CB · 2025Article
- Rhythmic circuit function is more robust to changes in synaptic than intrinsic conductances.eLife · 2025Article
- Increased robustness and adaptation to simultaneous temperature and elevated extracellular potassium in the pyloric rhythm of the crab,Journal of neurophysiology · 2025Article
- IeLife · 2024Article
- IbioRxiv : the preprint server for biology · 2024Article
- Resilience of circuits to environmental challenge.Current opinion in neurobiology · 2024Review
- Modulation of neuronal dynamics by sustained and activity-dependent continuous-wave near-infrared laser stimulation.Neurophotonics · 2024Article
- Alterations in network robustness upon simultaneous temperature and pH perturbations.Journal of neurophysiology · 2024Article
- Temporal scaling of motor cortical dynamics reveals hierarchical control of vocal production.Nature neuroscience · 2024Article
- Neurobiology and Changing Ecosystems: Mechanisms Underlying Responses to Human-Generated Environmental Impacts.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Interdependence of cellular and network properties in respiratory rhythmogenesis.bioRxiv : the preprint server for biology · 2023Article
- A biophysical perspective on the resilience of neuronal excitability across timescales.Nature reviews. Neuroscience · 2023Review
- Using temperature to analyze the neural basis of a time-based decision.Nature neuroscience · 2023Article
36 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors.
Funding
Abstract
Most animal species are cold-blooded, and their neuronal circuits must maintain function despite environmental temperature fluctuations. The central pattern generating circuits that produce rhythmic motor patterns depend on the orderly activation of circuit neurons. We describe the effects of temperature on the pyloric rhythm of the stomatogastric ganglion of the crab, Cancer borealis. The pyloric rhythm is a triphasic motor pattern in which the Pyloric Dilator (PD), Lateral Pyloric (LP), and Pyloric (PY) neurons fire in a repeating sequence. While the frequency of the pyloric rhythm increased about 4-fold (Q(10) approximately 2.3) as the temperature was shifted from 7 degrees C to 23 degrees C, the phase relationships of the PD, LP, and PY neurons showed almost perfect temperature compensation. The Q(10)'s of the input conductance, synaptic currents, transient outward current (I(A)), and the hyperpolarization-activated inward current (I(h)), all of which help determine the phase of LP neuron activity, ranged from 1.8 to 4. We studied the effects of temperature in >1,000 computational models (with different sets of maximal conductances) of a bursting neuron and the LP neuron. Many bursting models failed to monotonically increase in frequency as temperature increased. Temperature compensation of LP neuron phase was facilitated when model neurons' currents had Q(10)'s close to 2. Together, these data indicate that although diverse sets of maximal conductances may be found in identified neurons across animals, there may be strong evolutionary pressure to restrict the Q(10)'s of the processes that contribute to temperature compensation of neuronal circuits.
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