ReviewCurrent opinion in pharmacology2010
SnoN in mammalian development, function and diseases.
Review in Current opinion in pharmacology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Combining single-cell and bulk RNA sequencing, NK cell marker genes reveal a prognostic and immune status in pancreatic ductal adenocarcinoma.Scientific reports · 2024Article
- Blood glucose control contributes to protein stability of Ski-related novel protein N in a rat model of diabetes.Experimental and therapeutic medicine · 2021Article
- Role of macrophages in fetal development and perinatal disorders.Pediatric research · 2021Review
- The regulatory protein SnoN antagonizes activin/Smad2 protein signaling and thereby promotes adipocyte differentiation and obesity in mice.The Journal of biological chemistry · 2018Article
- BMP-7 enhances SnoN mRNA expression in renal tubular epithelial cells under high-glucose conditions.Molecular medicine reports · 2017Article
- SnoN Antagonizes the Hippo Kinase Complex to Promote TAZ Signaling during Breast Carcinogenesis.Developmental cell · 2016Article
- Smad7 interrupts TGF-β signaling in intestinal macrophages and promotes inflammatory activation of these cells during necrotizing enterocolitis.Pediatric research · 2016Article
- Invited review: mesenchymal progenitor cells in intramuscular connective tissue development.Animal : an international journal of animal bioscience · 2016Review
- The influence of SnoN gene silencing by siRNA on the cell proliferation and apoptosis of human pancreatic cancer cells.Diagnostic pathology · 2015Article
- PMA induces SnoN proteolysis and CD61 expression through an autocrine mechanism.Cellular signalling · 2014Article
- The diverse roles of calcium-binding protein regucalcin in cell biology: from tissue expression and signalling to disease.Cellular and molecular life sciences : CMLS · 2014Review
- The proteasome inhibitor, MG132, attenuates diabetic nephropathy by inhibiting SnoN degradation in vivo and in vitro.BioMed research international · 2014Article
- SnoN facilitates ALK1-Smad1/5 signaling during embryonic angiogenesis.The Journal of cell biology · 2013Article
- Genetic lineages of undifferentiated-type gastric carcinomas analysed by unsupervised clustering of genomic DNA microarray data.BMC medical genomics · 2013Article
- Smad7 inhibits autocrine expression of TGF-β2 in intestinal epithelial cells in baboon necrotizing enterocolitis.American journal of physiology. Gastrointestinal and liver physiology · 2013Article
- Expression profiles of SnoN in normal and cancerous human tissues support its tumor suppressor role in human cancer.PloS one · 2013Article
- SnoN activates p53 directly to regulate aging and tumorigenesis.Aging cell · 2012Article
- SnoN regulates mammary gland alveologenesis and onset of lactation by promoting prolactin/Stat5 signaling.Development (Cambridge, England) · 2012Article
- Drosophila CORL is required for Smad2-mediated activation of Ecdysone Receptor expression in the mushroom body.Development (Cambridge, England) · 2012Article
- SnoN in regulation of embryonic development and tissue morphogenesis.FEBS letters · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
SnoN (Ski-novel protein) was discovered as a nuclear proto-oncogene on the basis of its ability to induce transformation of chicken and quail embryonic fibroblasts. As a crucial negative regulator of transforming growth factor-β (TGF-β) signaling and also an activator of p53, it plays an important role in regulating cell proliferation, senescence, apoptosis, and differentiation. Recent studies of its expression patterns and functions in mouse models and mammalian cells have revealed important functions of SnoN in normal epithelial development and tumorigenesis. Evidence suggests that SnoN has both pro-oncogenic and anti-oncogenic functions by modulating multiple signaling pathways. These studies suggest that SnoN may have broad functions in the development and homeostasis of embryonic and postnatal tissues.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.