ReviewGenetica2011
Developing transgenic Anopheles mosquitoes for the sterile insect technique.
Review in Genetica, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 58 citations in OpenAlex.
- Compound effector genes suppress malaria parasite infections in gene-drive population modification strains of the African malaria mosquitoes, Anopheles gambiae and Anopheles coluzzii.G3 (Bethesda, Md.) · 2026Article
- The complex swarming dynamics of malaria mosquitoes emerge from simple minimally-interactive behavioral rules.PLoS computational biology · 2026Article
- Targeting the Highly Invasive Malaria Vector Anopheles stephensi using Yeast RNAi Pesticides.Research square · 2026Article
- Requirements for designing cluster randomised control trials to detect suppression of malaria vector population densities.BMC biology · 2025Article
- Spatial and temporal characteristics of laboratory-inducediScience · 2024Article
- Efficient sex separation by exploiting differential alternative splicing of a dominant marker in Aedes aegypti.PLoS genetics · 2023Article
- Characterization of lab-based swarms of Anopheles gambiae mosquitoes using 3D-video tracking.Scientific reports · 2023Article
- Life-history traits of a fluorescent Anopheles arabiensis genetic sexing strain introgressed into South African genomic background.Malaria journal · 2022Article
- The development of complex and controversial innovations. Genetically modified mosquitoes for malaria eradication.Research policy · 2020Article
- The impact of Anopheles gambiae egg storage for mass rearing and production success.Malaria journal · 2019Article
- Molecular tools and genetic markers for the generation of transgenic sexing strains in Anopheline mosquitoes.Parasites & vectors · 2018Review
- Impact of mosquito gene drive on malaria elimination in a computational model with explicit spatial and temporal dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Evidence for temporal population replacement and the signature of ecological adaptation in a major Neotropical malaria vector in Amazonian Peru.Malaria journal · 2015Article
- Modelling sterile insect technique to control the population of Anopheles gambiae.Malaria journal · 2015Article
- Review
- Genetic approaches to interfere with malaria transmission by vector mosquitoes.Trends in biotechnology · 2013Review
- Targeting gene expression to the female larval fat body of transgenic Aedes aegypti mosquitoes.Insect molecular biology · 2013Article
- Article
- Fitness of transgenic mosquito Aedes aegypti males carrying a dominant lethal genetic system.PloS one · 2013Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the last 10 years the availability of the genome sequence of Anopheles gambiae and the development of a transgenic technology for several species of Anopheles mosquitoes have, in combination, helped in enabling us to gain several insights into the biology of these mosquitoes that is relevant to their capacity as vectors of the malaria parasite. While this information is anticipated to inform many novel vector control strategies, the technique most likely to benefit in the near future from the availability of a reliable transgenic technology is the sterile insect technique (SIT), which relies on releasing large numbers of sterile insects to compete for mates in the wild, leading to population suppression. Although SIT has been proven to work reliably for many insects, the construction of suitable strains, and induction of sterility, has until now been a laborious process, combining classical genetics with radiation-induced sterility. Using transgenesis to create strains of Anopheles suitable for SIT could potentially offer several advantages over current approaches, in that the basic design of transgenic constructs designed for other insects should be rapidly transferable to mosquitoes, and induction of sterility as a product of the transgenic modification could obviate the requirement for radiation and its associated deleterious effects. In this paper the progress of different transgenic approaches in constructing tools for SIT will be reviewed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.