ArticleLasers in medical science2011
Numerical investigation of nanoparticle-assisted laser-induced interstitial thermotherapy toward tumor and cancer treatments.
Article in Lasers in medical science, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 55 citations in OpenAlex.
- Nanoparticle enhanced coupled bioheat vapor bubble model and simulation for LITT in breast tumors.Lasers in medical science · 2025Article
- Nanoparticle-assisted, image-guided laser interstitial thermal therapy for cancer treatment.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2022Review
- Thermal field and tissue damage analysis of moving laser in cancer thermal therapy.Lasers in medical science · 2021Article
- Multiphysics Modeling of Plasmonic Photothermal Heating Effects in Gold Nanoparticles and Nanoparticle Arrays.The journal of physical chemistry. C, Nanomaterials and interfaces · 2020Article
- Potentials and pitfalls of gold-silica nanoshell as the exogenous contrast agent for optical diagnosis of cancers: a numerical parametric study.Lasers in medical science · 2019Article
- Evaluation of theranostic perspective of gold-silica nanoshell for cancer nano-medicine: a numerical parametric study.Lasers in medical science · 2019Article
- Feasibility of selective nanoparticle-assisted photothermal treatment for an embedded liver tumor.Lasers in medical science · 2013Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this work, we numerically investigated nanoparticle-assisted laser-induced interstitial thermotherapy for tumor/cancer treatments. The goal of the study was to investigate the therapeutic effects of treatment conditions including laser wavelength, power, exposure time, concentrations of tailored nanoparticles, and optical/thermal properties of the tissue that is under treatment. It was found that using absorbing preferential nanoparticles as the photothermal agent weakens fluence rate distributions in terms of lowering fluence rate peaks and reducing laser penetration depths. However, the local enhancement in laser photon absorption induced by nanoparticles is so significant that the reduced fluence rate will be balanced out, and the eventual medical hyperthermia is greatly prompted by using nanoparticles. Also, the results of numerical simulations indicated that with constant laser illumination, an increase in nanoparticle concentration beyond a certain range has only an insignificant impact on hyperthermia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.