ArticleEuropean archives of psychiatry and clinical neuroscience2011
Olfactory identification and preference in bipolar disorder and schizophrenia.
Article in European archives of psychiatry and clinical neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Changes in olfactory function and serum interleukin-6 levels in the acute phase of bipolar I disorder: a longitudinal study.BMC psychiatry · 2025Article
- Inflammation-related pathology in the olfactory epithelium: its impact on the olfactory system in psychotic disorders.Molecular psychiatry · 2024Article
- Significant improvements in the olfactory sensitivity of bipolar I disorder patients during euthymia versus manic episodes: a longitudinal study.Frontiers in psychiatry · 2024Article
- Comparison of olfactory function, cognitive function and serum tumor necrosis factor-α between bipolar and schizophrenic patients in the remission stage.BMC psychiatry · 2023Article
- Functionality appreciation is inversely associated with positive psychotic symptoms in overweight/obese patients with schizophrenia.BMC psychiatry · 2023Article
- Brain regions associated with olfactory dysfunction in first episode psychosis patients.The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2023Article
- Odor Hedonic Profile (OHP): a self-rating tool of everyday odors.Frontiers in neuroscience · 2023Article
- Impaired olfactory function in bipolar disorder patients during acute episodes regardless of psychotic symptoms.Frontiers in psychiatry · 2023Article
- Variations in olfactory function among bipolar disorder patients with different episodes and subtypes.Frontiers in psychiatry · 2023Article
- Pleasant and unpleasant odor identification ability is associated with distinct dimensions of negative symptoms transdiagnostically in psychotic disorders.Schizophrenia research · 2022Article
- Olfactory modulation of the medial prefrontal cortex circuitry: Implications for social cognition.Seminars in cell & developmental biology · 2022Review
- Olfactory impairment in psychiatric disorders: Does nasal inflammation impact disease psychophysiology?Translational psychiatry · 2022Review
- Sex Differences in Odor Hedonic Perception: An Overview.Frontiers in neuroscience · 2021Review
- Chemosensory Anhedonia in Patients With Schizophrenia and Individuals With Schizotypy: A Questionnaire Study.Frontiers in psychiatry · 2020Article
- Overrated hedonic judgment of odors in patients with schizophrenia.CNS neuroscience & therapeutics · 2018Article
- Sex differences in hedonic judgement of odors in schizophrenia cases and healthy controls.Psychiatry research · 2018Article
- Olfactory Functioning in First-Episode Psychosis.Schizophrenia bulletin · 2018Article
- Olfactory Functioning and Depression: A Systematic Review.Frontiers in psychiatry · 2017Review
- Current smoking is associated with worse cognitive and adaptive functioning in serious mental illness.Acta psychiatrica Scandinavica · 2015Article
- The Evaluation of Olfactory Function in Patients With Schizophrenia.Global journal of health science · 2015Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Olfactory identification deficit appears to be an enduring feature of schizophrenia, but it is unclear whether it is specific to schizophrenia or present in psychotic disorders in general. The aim of the present study was to compare olfactory identification and olfactory preference in schizophrenia and bipolar disorder. Individuals with schizophrenia or bipolar disorder and demographically matched healthy participants were given the University of Pennsylvania Smell Identification Test (UPSIT) to assess olfactory identification ability. To examine olfactory hedonic judgment, participants were also asked to indicate their preference for each UPSIT item on a 5-point rating scale, immediately after odor identification. Clinical symptoms and social competence were also assessed. Both schizophrenic and bipolar groups showed olfactory identification deficits compared with the healthy controls, but schizophrenic patients were more impaired than bipolar patients on the UPSIT accuracy. Interestingly, both bipolar and schizophrenic patients rated odors to be more pleasant than did healthy controls, but all groups preferred odors that they could correctly identify to unidentified smells. Restricted range of preference ratings was associated with the severity of negative symptoms in schizophrenia, and with mania in bipolar disorder. Social competence was associated with better olfactory identification performance. These findings suggest that olfactory identification and preference are compromised in bipolar disorder as well as in schizophrenia, but the precise nature of these abnormalities needs to be further elucidated.
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