Evidence map›Paper›PMID 20820467›Full record

ReviewChemical Society reviews2010

Arylethynyl receptors for neutral molecules and anions: emerging applications in cellular imaging.

Calden N Carroll, John J Naleway, Michael M Haley, Darren W Johnson

Abstract readReview
In one paragraph

Review in Chemical Society reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. A Synthetic Supramolecular Receptor for the Hydrosulfide Anion.Angewandte Chemie (International ed. in English) · 2016
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Aryl C-H···Cl(-) hydrogen bonding in a fluorescent anion sensor.Chemical communications (Cambridge, England) · 2013
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Calden N CarrollDepartment of Chemistry and the Materials Science Institute, 1253 University of Oregon, Eugene, OR 97403-1253, USA.
John J Naleway
Michael M Haley
Darren W Johnson

Funding

Design of Modular Receptors for Ion and Molecule RecognitionR01GM087398 · NIGMS · UNIVERSITY OF OREGON · PI HALEY, MICHAEL MARK, JOHNSON, DARREN WILLIAM · 2010 to 2020
$2.6M
NIGMS NIH HHS GM087398-01A1NIGMS NIH HHS R01 GM087398
6 · The paper itself

Abstract

This critical review will focus on the application of shape-persistent receptors for anions that derive their rigidity and optoelectronic properties from the inclusion of arylethynyl linkages. It will highlight a few of the design strategies involved in engineering selective and sensitive fluorescent probes and how arylacetylenes can offer a design pathway to some of the more desirable properties of a selective sensor. Additionally, knowledge gained in the study of these receptors in organic media often leads to improved receptor design and the production of chromogenic and fluorogenic probes capable of detecting specific substrates among the multitude of ions present in biological systems. In this ocean of potential targets exists a large number of geometrically distinct anions, which present their own problems to the design of receptors with complementary binding for each preferred coordination geometry. Our interest in targeting charged substrates, specifically how previous work on receptors for cations or neutral guests can be adapted to anions, will be addressed. Additionally, we will focus on the design and development of supramolecular arylethynyl systems, their shape-persistence and fluorogenic or chromogenic optoelectronic responses to complexation. We will also examine briefly how the "chemistry in the cuvet" translates into biological media (125 references).

Indexed as

AcetyleneAnimalsAnionsCrystallography, X-RayFluorescent DyesMiceMicroscopy, FluorescenceMolecular ConformationNIH 3T3 CellsPositron-Emission TomographyAcetyleneAnionsFluorescent Dyesphenylacetylene

Identifiers

PMID20820467
PMCPMC3062433

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.