ArticleThe Journal of cell biology2010
NPHP proteins: gatekeepers of the ciliary compartment.
Article in The Journal of cell biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 42 citations in OpenAlex.
- Deciphering vesicle-assisted transport mechanisms in cytoplasm to cilium trafficking.Frontiers in cellular neuroscience · 2024Review
- Rpgrip1l controls ciliary gating by ensuring the proper amount of Cep290 at the vertebrate transition zone.Molecular biology of the cell · 2021Article
- Defective INPP5E distribution in NPHP1-related Senior-Loken syndrome.Molecular genetics & genomic medicine · 2021Article
- Whole exome sequencing identified a homozygous novel variant in CEP290 gene causes Meckel syndrome.Journal of cellular and molecular medicine · 2020Article
- Targeted exon skipping rescues ciliary protein composition defects in Joubert syndrome patient fibroblasts.Scientific reports · 2019Article
- The Role of Primary Cilia in the Crosstalk between the Ubiquitin⁻Proteasome System and Autophagy.Cells · 2019Review
- Cell type-specific regulation of ciliary transition zone assembly in vertebrates.The EMBO journal · 2018Article
- Ciliopathies.Cold Spring Harbor perspectives in biology · 2017Review
- IFT-Cargo Interactions and Protein Transport in Cilia.Trends in biochemical sciences · 2015Review
- NINL and DZANK1 Co-function in Vesicle Transport and Are Essential for Photoreceptor Development in Zebrafish.PLoS genetics · 2015Article
- DNA replication stress underlies renal phenotypes in CEP290-associated Joubert syndrome.The Journal of clinical investigation · 2015Article
- Article
- Nephronophthisis and related syndromes.Current opinion in pediatrics · 2015Review
- Tubulin transport by IFT is upregulated during ciliary growth by a cilium-autonomous mechanism.The Journal of cell biology · 2015Article
- The primary cilium: guardian of organ development and homeostasis.Organogenesis · 2014Review
- Article
- The Nek8 protein kinase, mutated in the human cystic kidney disease nephronophthisis, is both activated and degraded during ciliogenesis.Human molecular genetics · 2012Article
- Dilatory is a Drosophila protein related to AZI1 (CEP131) that is located at the ciliary base and required for cilium formation.Journal of cell science · 2011Article
- Regulating the transition from centriole to basal body.The Journal of cell biology · 2011Review
- The Ran importin system in cilia trafficking.OrganogenesisArticle
Corrections and comments
- Comment on
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cilia and the cytoplasm are separated by a region called the transition zone, where wedge-shaped structures link the microtubule doublets of the axoneme to the ciliary membrane, thereby forming a ciliary "gate." In this issue, Craige et al. (J. Cell Biol. doi:10.1083/jcb.201006105) demonstrate in Chlamydomonas reinhardtii that Nphp6/cep290, which is mutated in nephronophthisis (NPHP), is an integral component of these connectors and maintains the structural integrity of this gate.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.