Evidence map›Paper›PMID 20819859›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA

Extracting Rx information from clinical narrative.

James G Mork, Olivier Bodenreider, Dina Demner-Fushman, Rezarta Islamaj Dogan, François-Michel Lang, Zhiyong Lu, Aurélie Névéol, Lee Peters, Sonya E Shooshan, Alan R Aronson

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Clinical concept extraction: A methodology review.Journal of biomedical informatics · 2020
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Automating annotation of information-giving for analysis of clinical conversation.Journal of the American Medical Informatics Association : JAMIA · 2014
    Article
  11. tmBioC: improving interoperability of text-mining tools with BioC.Database : the journal of biological databases and curation · 2014
    Article
  12. Article
  13. Clinical research informatics: a conceptual perspective.Journal of the American Medical Informatics Association : JAMIA · 2012
    Article
  14. Article
  15. Article
  16. MedXN: an open source medication extraction and normalization tool for clinical text.Journal of the American Medical Informatics Association : JAMIA
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

James G MorkUS National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.
Olivier Bodenreider
Dina Demner-Fushman
Rezarta Islamaj Dogan
François-Michel Lang
Zhiyong Lu
Aurélie Névéol
Lee Peters
Sonya E Shooshan
Alan R Aronson

Funding

National Biomedical Information ServicesZIHLM200888 · NLM · NATIONAL LIBRARY OF MEDICINE · PI PALTOO, DINA · 2009 to 2025
$5200.7M
Informatics for Integrating Biology/ the Bedside (RMI)U54LM008748 · NLM · BRIGHAM AND WOMEN'S HOSPITAL · PI KOHANE, ISAAC S. · 2004 to 2013
$39.0M
Named Entity Recognition and Relationship Extraction in BiomedicineZIALM000002 · NLM · NATIONAL LIBRARY OF MEDICINE · PI LU, ZHIYONG · 2011 to 2012
$1.5M
PubMed Query Log Analysis and Use in Access InhancementZIALM200812 · NLM · NATIONAL LIBRARY OF MEDICINE · PI WILBUR, WILLY · 2009 to 2015
$1.4M
Intramural NIH HHS Z99 LM999999NLM NIH HHS U54 LM008748NLM NIH HHS U54LM008748
6 · The paper itself

Abstract

objectiveThe authors used the i2b2 Medication Extraction Challenge to evaluate their entity extraction methods, contribute to the generation of a publicly available collection of annotated clinical notes, and start developing methods for ontology-based reasoning using structured information generated from the unstructured clinical narrative.

designExtraction of salient features of medication orders from the text of de-identified hospital discharge summaries was addressed with a knowledge-based approach using simple rules and lookup lists. The entity recognition tool, MetaMap, was combined with dose, frequency, and duration modules specifically developed for the Challenge as well as a prototype module for reason identification. MEASUREMENTS: Evaluation metrics and corresponding results were provided by the Challenge organizers.

resultsThe results indicate that robust rule-based tools achieve satisfactory results in extraction of simple elements of medication orders, but more sophisticated methods are needed for identification of reasons for the orders and durations. LIMITATIONS: Owing to the time constraints and nature of the Challenge, some obvious follow-on analysis has not been completed yet.

conclusionsThe authors plan to integrate the new modules with MetaMap to enhance its accuracy. This integration effort will provide guidance in retargeting existing tools for better processing of clinical text.

Indexed as

Electronic Health RecordsNatural Language ProcessingPharmaceutical PreparationsHumansInformation Storage and RetrievalPatient DischargeSoftware DesignPharmaceutical Preparations

Identifiers

PMID20819859
PMCPMC2995679

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.