ArticleWorld journal of gastroenterology2010
HCV genotype distribution and possible transmission risks in Lahore, Pakistan.
Article in World journal of gastroenterology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- Hepatitis C virus prevalence and genotype distribution in Pakistan: Comprehensive review of recent data.World journal of gastroenterology · 2016Pooled it
- Recent updates on molecular epidemiology of hepatitis C virus in Gujranwala, Pakistan.African health sciences · 2024Article
- Article
- Detection, quantification and genotype distribution of HCV patients in Lahore, Pakistan by real-time PCR.African health sciences · 2020Article
- Review on the molecular epidemiology of sexually acquired hepatitis C virus infection in the Asia-Pacific region.Journal of the International AIDS Society · 2020Review
- HCV infection causes cirrhosis in human by step-wise regulation of host genes involved in cellular functioning and defense during fibrosis: Identification of bio-markers.Genes & diseases · 2019Article
- Molecular characterization and clinical epidemiology of HCV in District Dir (Lower), Pakistan.Virusdisease · 2018Article
- Prevalence of hepatitis-C virus genotypes and potential transmission risks in Malakand Khyber Pakhtunkhwa, Pakistan.Virology journal · 2017Article
- Prevalence of Hepatitis C Virus Genotypes Among Patients in Countries of the Eastern Mediterranean Regional Office of WHO (EMRO): A Systematic Review and Meta-Analysis.Hepatitis monthly · 2016Review
- Age and gender distribution of Hepatitis C virus prevalence and genotypes of individuals of physical examination in WuHan, Central China.SpringerPlus · 2016Article
- Article
- Correlation Study Between HCV Genotypes Distribution Pattern and Viral Load in a Tertiary Care Hospital in Kolkata, India.Journal of clinical and diagnostic research : JCDR · 2015Article
- Diagnostically untypable hepatitis C virus variants: it is time to resolve the problem.World journal of gastroenterology · 2014Article
- Molecular epidemiology and viral load of HCV in different regions of Punjab, Pakistan.Virology journal · 2014Article
- Prevalence of active hepatitis C virus infections among general public of Lahore, Pakistan.Virology journal · 2013Article
- The first complete genome sequence of HCV-1a from Pakistan and a phylogenetic analysis with complete genomes from the rest of the world.Virology journal · 2013Article
- Prevalence of HCV genotypes in district Mardan.Virology journal · 2013Article
- Development of persistent HCV genotype 3a infection cell culture model in huh-7 cell.Virology journal · 2012Article
- Determination of HCV genotypes and viral loads in chronic HCV infected patients of Hazara Pakistan.Virology journal · 2011Article
- Identification of ionotrophic purinergic receptors in Huh-7 cells and their response towards structural proteins of HCV genotype 3a.Virology journal · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the prevalence of hepatitis C virus (HCV) genotypes and their association with possible transmission routes in the general population of Lahore, as the data exclusively related to this city is limited.
methodsComplete data regarding patient's history, possible route of infection and biochemical tests was collected from the public hospital for 1364 patients. SPSS version 16 windows software was used for data analysis by univariate and multivariate techniques.
resultsAge range < or = 40 years showed high prevalence of HCV infection. HCV genotype 3a was dominant (55.9%), followed by 1a (23.6%), 4a (12.5%), 3b (3.2%), untypable (2.5%), 4b (1.2%) and mixed type (1.2%). Blood transfusion, dental surgery and barber shops were the main risk factors for HCV transmission. Genotype prevalence was independent of age (P = 0.971) and gender (P = 0.122) while risk factors showed a significant association with age (P = 0.000) and genotypes (P = 0.000). We observed an independent association of risk factors and genotype 3a, while patients with genotype 1 and 4 were mostly infected due to dental surgery blood transfusion and barber shops. Risk factors of intravenous drug use and sexual exposure were exclusively found in < or = 40 years age group.
conclusionAn increase in genotypes 1a and 4a suggest migration of people, possibly from Balochistan and the northern war-zone area. Government should focus on public education regarding infection routes.
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Registered trials
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