Evidence map›Paper›PMID 20818724›Full record

ArticleDevelopmental disabilities research reviews2010

Historical perspective on mitochondrial medicine.

Salvatore DiMauro, Caterina Garone

Abstract readHistorical Article
In one paragraph

Article in Developmental disabilities research reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. De NovoInternational journal of molecular sciences · 2024
    Article
  4. Review
  5. Review
  6. Intimate Relations-Mitochondria and Ageing.International journal of molecular sciences · 2020
    Review
  7. The Dimensions of Primary Mitochondrial Disorders.Frontiers in cell and developmental biology · 2020
    Review
  8. Article
  9. Review
  10. Article
  11. Syndromes associated with mitochondrial DNA depletion.Italian journal of pediatrics · 2014
    Review
  12. Article
  13. Molecular genetic testing for mitochondrial disease: from one generation to the next.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2013
    Review
  14. Article
  15. Mitochondrial disorders and the eye.Current opinion in ophthalmology · 2011
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Salvatore DiMauroColumbia University Medical Center, College of Physicians & Surgeons, 630 West 168th Street, New York, NY 10032, USA. sd12@columbia.edu
Caterina Garone

Funding

THERAPEUTIC APPROACHES IN MODELS OF MITOCHONDRIAL DIS.P01HD032062 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DIMAURO, SALVATORE · 1995 to 2014
$24.4M
NICHD NIH HHS HD 32062NICHD NIH HHS P01 HD032062
6 · The paper itself

Abstract

In this review, we trace the origins and follow the development of mitochondrial medicine from the premolecular era (1962-1988) based on clinical clues, muscle morphology, and biochemistry into the molecular era that started in 1988 and is still advancing at a brisk pace. We have tried to stress conceptual advances, such as endosymbiosis, uniparental inheritance, intergenomic signaling and its defects, and mitochondrial dynamics. We hope that this historical review also provides an update on mitochondrial medicine, although we fully realize that the speed of progress in this area makes any such endeavor akin to writing on water.

Indexed as

Developmental DisabilitiesDNA, MitochondrialHistory, 20th CenturyHumansMitochondrial DiseasesDNA, Mitochondrial

Identifiers

PMID20818724
PMCPMC3839238

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.