Evidence map›Paper›PMID 20818415›Full record

ReviewNature reviews. Microbiology2010

Interactions between bacterial pathogens and mitochondrial cell death pathways.

Thomas Rudel, Oliver Kepp, Vera Kozjak-Pavlovic

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed.

  1. Review
  2. Environmental science. Processes & impacts · 2026
    Article
  3. Article
  4. Article
  5. The Virulence Factor LLO ofFoods (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Necroptosis in bacterial infections.Frontiers in immunology · 2024
    Review
  12. Infection and immunity · 2023
    Article
  13. Mitochondrial Dysfunction in Bacterial Infections.Pathogens (Basel, Switzerland) · 2023
    Review
  14. Article
  15. Article
  16. bioRxiv : the preprint server for biology · 2023
    Article
  17. Review
  18. Review
  19. Article
  20. Map of EnteropathogenicInternational journal of molecular sciences · 2022
    Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Thomas RudelLehrstuhl für Mikrobiologie, Biozentrum der Universität Würzburg, Germany. thomas.rudel@biozentrum.uni-wuerzburg.de
Oliver Kepp
Vera Kozjak-Pavlovic

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The modulation of host cell death pathways by bacteria has been recognized as a major pathogenicity mechanism. Among other strategies, bacterial pathogens can hijack the cell death machinery of host cells by influencing the signalling pathways that converge on the mitochondria. In particular, many bacterial proteins have evolved to interact in a highly specific manner with host mitochondria, thereby modulating the decision between cell life and death. In this Review, we explore the intimate interactions between bacterial pathogens and mitochondrial cell death pathways.

Indexed as

BacteriaAnimalsApoptosisBacterial ProteinsCell DeathHost-Pathogen InteractionsHumansMitochondriaSignal TransductionBacterial Proteins

Identifiers

PMID20818415

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.