ArticleJournal of bacteriology2010
Characterization of a two-component regulatory system that regulates succinate-mediated catabolite repression in Sinorhizobium meliloti.
Article in Journal of bacteriology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Article
- MostmSphere · 2018Article
- Transcriptome analysis and anaerobic CMicrobiologyOpen · 2018Article
- Article
- Transcriptomic analysis of a classical model of carbon catabolite regulation in Streptomyces coelicolor.BMC microbiology · 2016Article
- The flagellar set Fla2 in Rhodobacter sphaeroides is controlled by the CckA pathway and is repressed by organic acids and the expression of Fla1.Journal of bacteriology · 2015Article
- Site-Specific Ser/Thr/Tyr Phosphoproteome of Sinorhizobium meliloti at Stationary Phase.PloS one · 2015Article
- Complex two-component signaling regulates the general stress response in Alphaproteobacteria.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Analysis of a taurine-dependent promoter in Sinorhizobium meliloti that offers tight modulation of gene expression.BMC microbiology · 2014Article
- Benzoate mediates the simultaneous repression of anaerobic 4-methylbenzoate and succinate utilization in Magnetospirillum sp. strain pMbN1.BMC microbiology · 2014Article
- Automated system for kinetic analysis of particle size distributions for pharmaceutically relevant systems.Journal of analytical methods in chemistry · 2014Article
- Nuclear magnetic resonance structure and dynamics of the response regulator Sma0114 from Sinorhizobium meliloti.Biochemistry · 2012Article
- Benzoate mediates repression of C(4)-dicarboxylate utilization in "Aromatoleum aromaticum" EbN1.Journal of bacteriology · 2012Article
- Article
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Authors and funding
4 authors.
Funding
Abstract
When they are available, Sinorhizobium meliloti utilizes C(4)-dicarboxylic acids as preferred carbon sources for growth while suppressing the utilization of some secondary carbon sources such as α- and β-galactosides. The phenomenon of using succinate as the sole carbon source in the presence of secondary carbon sources is termed succinate-mediated catabolite repression (SMCR). Genetic screening identified the gene sma0113 as needed for strong SMCR when S. meliloti was grown in succinate plus lactose, maltose, or raffinose. sma0113 and the gene immediately downstream, sma0114, encode the proteins Sma0113, an HWE histidine kinase with five PAS domains, and Sma0114, a CheY-like response regulator lacking a DNA-binding domain. sma0113 in-frame deletion mutants show a relief of catabolite repression compared to the wild type. sma0114 in-frame deletion mutants overproduce polyhydroxybutyrate (PHB), and this overproduction requires sma0113. Sma0113 may use its five PAS domains for redox level or energy state monitoring and use that information to regulate catabolite repression and related responses.
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