Evidence map›Paper›PMID 20816906›Full record

ReviewAdvanced drug delivery reviews2010

Methods to assess stem cell lineage, fate and function.

Patricia K Nguyen, Divya Nag, Joseph C Wu

Abstract readReview
In one paragraph

Review in Advanced drug delivery reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Frontiers in cell and developmental biology · 2024
    Review
  6. Review
  7. Article
  8. Review
  9. Structural parameters of nanoparticles affecting their toxicity for biomedical applications: a review.Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology · 2023
    Review
  10. Article
  11. Injectable amnion hydrogel-mediated delivery of adipose-derived stem cells for osteoarthritis treatment.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  12. Article
  13. Metabolomics and Cell Therapy in Diabetes Mellitus.International journal of molecular and cellular medicine · 2019
    Review
  14. Review
  15. Review
  16. Article
  17. Magnetic resonance imaging of transplanted stem cell fate in stroke.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2014
    Review
  18. Article
  19. Stem cell tracking with optically active nanoparticles.American journal of nuclear medicine and molecular imaging · 2013
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Patricia K NguyenDepartment of Medicine, Stanford University School of Medicine, CA 94305, USA.
Divya Nag
Joseph C Wu
Stanford University · US

Funding

Molecular Imaging of Cardiac Stem Cell TherapyR01EB009689 · NIBIB · STANFORD UNIVERSITY · PI WU, JOSEPH C. · 2010 to 2013
$1.4M
Molecular Imaging of Resident Cardiac Stem CellsRC1HL099117 · NHLBI · STANFORD UNIVERSITY · PI WU, JOSEPH C. · 2009 to 2010
$1000k
NHLBI NIH HHS HL099117NHLBI NIH HHS RC1 HL099117NIBIB NIH HHS EB009689NIBIB NIH HHS R01 EB009689
6 · The paper itself

Abstract

Stem cell therapy has the potential to regenerate injured tissue. For stem cells to achieve their full therapeutic potential, stem cells must differentiate into the target cell, reach the site of injury, survive, and engraft. To fully characterize these cells, evaluation of cell morphology, lineage specific markers, cell specific function, and gene expression must be performed. To monitor survival and engraftment, cell fate imaging is vital. Only then can organ specific function be evaluated to determine the effectiveness of therapy. In this review, we will discuss methods for evaluating the function of transplanted cells for restoring the heart, nervous system, and pancreas. We will also highlight the specific challenges facing these potential therapeutic areas.

Indexed as

Cell LineageStem Cell TransplantationAnimalsCell DifferentiationHeart DiseasesHematopoietic Stem CellsHumansNervous System DiseasesPancreatic DiseasesRegenerationStem Cells

Identifiers

PMID20816906
PMCPMC3078641
OpenAlexW2052344292

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.