ArticleExperimental neurology2010
The phrenic motor nucleus in the adult mouse.
Article in Experimental neurology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 50 citations in OpenAlex.
- The evidence for old age motor neuron death: A scoping review.Physiological reports · 2026Article
- Perineuronal Net Changes Reveal a Distinct Right and Left Spinal Phrenic Circuit.Journal of neurotrauma · 2025Article
- A cholinergic spinal pathway for the adaptive control of breathing.Cell reports · 2025Article
- Article
- A cholinergic spinal pathway for the adaptive control of breathing.bioRxiv : the preprint server for biology · 2025Article
- Inactivity-induced phrenic motor facilitation requires PKCζ activity within phrenic motor neurons.Journal of neurophysiology · 2024Article
- V2a neurons restore diaphragm function in mice following spinal cord injury.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Targeting drug or gene delivery to the phrenic motoneuron pool.Journal of neurophysiology · 2023Review
- Transneuronal tracing to map connectivity in injured and transplanted spinal networks.Experimental neurology · 2022Review
- Diaphragmatic Activity and Respiratory Function Following C3 or C6 Unilateral Spinal Cord Contusion in Mice.Biology · 2022Article
- Targeted activation of spinal respiratory neural circuits.Experimental neurology · 2020Review
- Phrenic motor neuron loss in an animal model of early onset hypertonia.Journal of neurophysiology · 2020Article
- Evolution and Functional Differentiation of the Diaphragm Muscle of Mammals.Comprehensive physiology · 2019Review
- Structural and functional identification of two distinct inspiratory neuronal populations at the level of the phrenic nucleus in the rat cervical spinal cord.Brain structure & function · 2019Article
- The Neuroplastic and Therapeutic Potential of Spinal Interneurons in the Injured Spinal Cord.Trends in neurosciences · 2018Review
- Breathing: Motor Control of Diaphragm Muscle.Physiology (Bethesda, Md.) · 2018Review
- Retrograde Neuroanatomical Tracing of Phrenic Motor Neurons in Mice.Journal of visualized experiments : JoVE · 2018Article
- Anatomical Recruitment of Spinal V2a Interneurons into Phrenic Motor Circuitry after High Cervical Spinal Cord Injury.Journal of neurotrauma · 2017Article
- The Therapeutic Effectiveness of Delayed Fetal Spinal Cord Tissue Transplantation on Respiratory Function Following Mid-Cervical Spinal Cord Injury.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2017Article
- Transcriptome assessment of the Pompe (Gaa-/-) mouse spinal cord indicates widespread neuropathology.Physiological genomics · 2016Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The present study was performed to establish an anatomical context for studies of phrenic motor function in mouse models of central nervous system trauma and disease. Application of cholera toxin β-subunit to the diaphragm of adult C57BL/6 mice revealed a columnar organization of phrenic motoneurons (PhMNs) which extended from rostral C3 to C6. Injection of Miniruby into the ventrolateral medulla revealed decussating, anterogradely labeled axons in the cervical spinal cord. In addition, application of the transneuronal tracer pseudorabies virus (PRV) to the right hemidiaphragm demonstrated a population of putative pre-phrenic interneurons at the level of the infected PhMN pool. These neuroanatomical features of the mouse phrenic nucleus are consistent with those described in other species and provide a foundation for studies of neuroplasticity and repair in relation to a functionally and anatomically identified spinal network.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.