Evidence map›Paper›PMID 20814997›Full record

ArticleAngewandte Chemie (International ed. in English)2010

Selective modulation of DNA polymerase activity by fixed-conformation nucleoside analogues.

Robert L Eoff, Colleen E McGrath, Leena Maddukuri, S Giovanna Salamanca-Pinzón, Victor E Marquez, Lawrence J Marnett, F Peter Guengerich, Martin Egli

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Robert L EoffDepartment of Biochemistry, Center in Molecular Toxicology and Vanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine, Nashville, TN 37232-0146, USA.
Colleen E McGrath
Leena Maddukuri
S Giovanna Salamanca-Pinzón
Victor E Marquez
Lawrence J Marnett
F Peter Guengerich
Martin Egli
Vanderbilt University · USFrederick National Laboratory for Cancer Research · US

Funding

Structural Biology Facility CoreP30ES000267 · NIEHS · VANDERBILT UNIVERSITY · PI GUENGERICH, F PETER · 1985 to 2014
$20.3M
SYNTHETIC APPROACHES TO PAH-ADDUCTED NUCLEOTIDESP01ES005355 · NIEHS · VANDERBILT UNIVERSITY · PI RIZZO, CARMELO J · 1991 to 2010
$13.4M
POLYMERASE INTERACTIONS WITH CARCINOGEN MODIFIED DNAR01ES010375 · NIEHS · VANDERBILT UNIVERSITY · PI GUENGERICH, F PETER · 2000 to 2014
$5.9M
Chemistry and Biology of Malondialdehyde DNA AdductsR37CA087819 · NCI · VANDERBILT UNIVERSITY · PI MARNETT, LAWRENCE J. · 2005 to 2014
$4.2M
Coordinating Translesion DNA Synthesis Opposite Damaged DNAK99GM084460 · NIGMS · VANDERBILT UNIVERSITY · PI EOFF, ROBERT L · 2009 to 2010
$111k
Intramural NIH HHSNCI NIH HHS R37 CA087819NIEHS NIH HHS P01 ES005355NIEHS NIH HHS P01 ES05355NIEHS NIH HHS P30 ES000267NIEHS NIH HHS R01 ES010375NIGMS NIH HHS K99 GM084460
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Base SequenceBreast NeoplasmsCell Line, TumorCell ProliferationDNADNA-Directed DNA PolymeraseFemaleGene Expression Regulation, NeoplasticHIV-1HIV Reverse TranscriptaseHumansMolecular ConformationNucleosidesDNADNA-Directed DNA PolymeraseHIV Reverse TranscriptaseNucleosides

Identifiers

PMID20814997
PMCPMC3011974
OpenAlexW2114315219

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.