ArticleJournal of natural medicines2011
Antiobesity effects of Kaempferia parviflora in spontaneously obese type II diabetic mice.
Article in Journal of natural medicines, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- Activation of Human Brown Adipose Tissue by Capsinoids, Catechins, Ephedrine, and Other Dietary Components: A Systematic Review.Advances in nutrition (Bethesda, Md.) · 2019Pooled it
- Clinical Effects of Krachaidum ( Kaempferia parviflora): A Systematic Review.Journal of evidence-based complementary & alternative medicine · 2017Pooled it
- Glucose Tolerance Test and Pharmacokinetic Study ofNutrients · 2019Trial
- Assessment of sub-chronic toxicity and anti-aging effects of a solid self-microemulsifying drug delivery system ofPharmaceutical biology · 2026Article
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- Oral delivery ofInternational journal of pharmaceutics: X · 2025Article
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- Exploring Volatile Organic Compounds in Rhizomes and Leaves ofMetabolites · 2023Article
- Kaempferia parviflora rhizome extract exerts anti-obesity effect in high-fat diet-induced obese C57BL/6N mice.Food & nutrition research · 2023Article
- Antiobesity effect ofFood & nutrition research · 2023Article
- The industrially important genusFrontiers in pharmacology · 2023Review
- Black Ginger (Nutrients · 2022Article
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- Protective Effect of Polymethoxyflavones Isolated fromAntioxidants (Basel, Switzerland) · 2021Article
- Establishment of a Rapid Micropropagation System forPlants (Basel, Switzerland) · 2021Article
- Kaempferia parviflora Nanosuspension Formulation for Scalability and Improvement of Dissolution Profiles and Intestinal Absorption.AAPS PharmSciTech · 2020Article
- Recent Advances inNutrients · 2019Review
- Toxicological evaluation of standardizedToxicology reports · 2019Article
- 5-Hydroxy-7-methoxyflavone derivatives fromFood science & nutrition · 2019Article
- Effect of the active ingredient of Kaempferia parviflora, 5,7-dimethoxyflavone, on the pharmacokinetics of midazolam.Journal of natural medicines · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Kaempferia parviflora Wall. Ex Baker (KP) has been used as a folk medicine in Laos and Thailand to lower blood glucose levels, improve blood flow, and increase vitality. This study investigated the preventive effects of KP on obesity and its downstream symptoms (various metabolic disorders) using Tsumura, Suzuki, Obese Diabetes (TSOD) mice, a multifactorial genetic disease animal model in which metabolic diseases develop spontaneously, similar to metabolic syndrome in humans, and Tsumura, Suzuki, Non-Obesity (TSNO) mice as the corresponding control mice. When feed that was mixed with KP (1 or 3%) was given ad libitum to TSOD and TSNO mice for 8 weeks, body weight increase, visceral fat accumulation, lipid metabolism abnormalities, hyperinsulinemia, glucose intolerance, insulin resistance, hypertension, and peripheral neuropathy were suppressed in TSOD mice, but no marked differences were observed in TSNO mice. Because KP had preventive effects on metabolic diseases, including antiobesity effects, only in obese animals, we propose that KP will be extremely valuable as a medicine or component of food in alternative health care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.