ArticleLasers in medical science2011
Frequency-domain near-infrared spectroscopy of the uterine cervix during regular pregnancies.
Article in Lasers in medical science, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Feasibility of Near-Infrared Spectroscopy for Monitoring Tissue Oxygenation During Uterus Transplantation and Hysterectomy.Journal of clinical medicine · 2025Article
- Review of recent advances in frequency-domain near-infrared spectroscopy technologies [Invited].Biomedical optics express · 2023Review
- Multi-modulated frequency domain high density diffuse optical tomography.Biomedical optics express · 2022Article
- Ultra-sensitive optical coherence elastography using a high-dynamic-range force loading scheme for cervical rigidity assessment.Biomedical optics express · 2020Article
- Development of a visually guided Raman spectroscopy probe for cervical assessment during pregnancy.Journal of biophotonics · 2019Article
- Quantitative Ultrasound Biomarkers Based on Backscattered Acoustic Power: Potential for Quantifying Remodeling of the Human Cervix during Pregnancy.Ultrasound in medicine & biology · 2019Article
- In vivo Raman spectroscopy for biochemical monitoring of the human cervix throughout pregnancy.American journal of obstetrics and gynecology · 2018Article
- In vivo Raman spectral analysis of impaired cervical remodeling in a mouse model of delayed parturition.Scientific reports · 2017Article
- Artificial neural networks for retrieving absorption and reduced scattering spectra from frequency-domain diffuse reflectance spectroscopy at short source-detector separation.Biomedical optics express · 2016Article
- Near-infrared low-level laser stimulation of telocytes from human myometrium.Lasers in medical science · 2014Article
- Raman spectroscopy provides a noninvasive approach for determining biochemical composition of the pregnant cervix in vivo.Acta paediatrica (Oslo, Norway : 1992) · 2014Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Preterm labor is a common obstetric complication. Clinical evaluation of cervical ripening to predict preterm labor is very inaccurate. We used frequency-domain near-infrared spectroscopy (FD-NIRS) to non-invasively investigate the changes of the optical properties (i.e., absorption and scattering of light) in the uterine cervix during regular pregnancies. Optical properties of uterine cervices were measured in 13 patients at various time points of regular pregnancies. For each gestational trimester, mean values with 95% confidence intervals were calculated for oxy-, deoxy-, and total hemoglobin concentration (O(2)Hb, HHb, tHb), tissue oxygen saturation and water content and statistically significant differences between the trimesters were determined. The wavelength-dependent scattering (scatter power) was calculated by an exponential fit. O(2)Hb, and tHb and the scatter power showed an increase as a function of the gestational age. Differences between the second and the third trimester were statistically significant. HHb and the water content showed no significant change over time. Our results show that FD-NIRS is a promising diagnostic tool for providing information about cervical content of hemoglobin, water, and extracellular matrix proteins. We propose this technology to assess the cervical ripening and eventually to predict preterm labor.
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Registered trials
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