ArticleEuropean journal of pediatrics2011
Transcutaneous bilirubin nomogram for predicting neonatal hyperbilirubinemia in healthy term and late-preterm Chinese infants.
Article in European journal of pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- [Guidelines for the diagnosis and treatment of common neonatal diseases in primary healthcare institutions: neonatal jaundice (2025)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025Guideline
- Bilirubin nomograms for identification of neonatal hyperbilirubinemia in healthy term and late-preterm infants: a systematic review and meta-analysis.World journal of pediatrics : WJP · 2014Pooled it
- Italian guidelines for management and treatment of hyperbilirubinaemia of newborn infants ≥ 35 weeks' gestational age.Italian journal of pediatrics · 2014Guideline
- Multidisciplinary guidelines for the care of late preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2013Guideline
- Accuracy and precision of transcutaneous bilirubinometry in postdischarge Asian neonates.European journal of pediatrics · 2013Trial
- Evolution and contemporary landscape of neonatal hyperbilirubinemia management guidelines: a narrative review.Frontiers in pediatrics · 2026Review
- Applicability of the hour of life approach in hyperbilirubinemia among Filipino term infants.Frontiers in pediatrics · 2022Article
- Natural history of early neonatal bilirubinemia: a global perspective.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Reliability of transcutaneous bilirubin determination based on skin color determined by a neonatal skin color scale of our own.European journal of pediatrics · 2021Observational
- Accuracy of enhanced transcutaneous bilirubinometry according to various measurement sites.Turkish archives of pediatrics · 2021Article
- Israel transcutaneous bilirubin nomogram predicts significant hyperbilirubinemia.Journal of perinatology : official journal of the California Perinatal Association · 2017Article
- Article
- Transcutaneous bilirubin nomograms in African neonates.PloS one · 2017Observational
- [Value of hour-specific transcutaneous bilirubin nomogram for prediction of hyperbilirubinemia in healthy neonates].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2016Article
- An hour-specific transcutaneous bilirubin nomogram for Mongolian neonates.European journal of pediatrics · 2015Article
- Association of UGT1A1 variants and hyperbilirubinemia in breast-fed full-term Chinese infants.PloS one · 2014Article
- Validation of a transcutaneous bilirubin meter in Mongolian neonates: comparison with total serum bilirubin.BMC pediatrics · 2013Article
- BiliCheck vs JM-103 in identifying neonates not at risk of hyperbilirubinaemia.Italian journal of pediatrics · 2013Article
- Development and validation of serum bilirubin nomogram to predict the absence of risk for severe hyperbilirubinaemia before discharge: a prospective, multicenter study.Italian journal of pediatrics · 2012Article
- Risk factors for hyperbilirubinemia in breastfed term neonates.European journal of pediatrics · 2012Article
Corrections and comments
- Commented on by
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Identifying infants that will develop significant hyperbilirubinemia with the risk of kernicterus, and planning appropriate follow-up strategies, is particularly challenging. In this study, 36,921 transcutaneous bilirubin (TcB) measurements were obtained from 6,035 healthy neonates (gestational age ≥ 35 weeks and birth weight ≥ 2,000 g) between January 1 and December 31, 2009. All measurements were performed with the JM-103 bilirubinometer at designated times between 0 and 168 postnatal hours. TcB percentiles were calculated and used to develop an hour-specific nomogram. The rate of increase in TcB was higher during the first 72 h of age, after which levels declined to a plateau by 72-108 h of age. We constructed a TcB nomogram by using the 40th, 75th, and 95th percentile values of TcB for every 12 h of the studied interval. The 75th percentile curve of the nomogram may be an ideal cutoff point for intensive follow-up of the neonate for hyperbilirubinemia as it carries very high sensitivity (78.7%) and negative predictive value (98.5%). The specificity (45.7%) and positive predictive value (15.5%) decreased to reach their lowest levels at the 40th percentile. Of the neonates in the high-risk zone, 167 (48.8%) infants had persistent subsequent hyperbilirubinemia post-discharge, compared with 292 (27.0%) infants in the high-intermediate-risk zone at discharge. One-hundred and seventeen (5.5%) infants in the low-intermediate-risk zone moved into the high-risk zone during follow-up. No newborn infants in the low-risk zone became high-risk during follow-up. We provide an hour-specific TcB nomogram to predict neonatal hyperbilirubinemia in healthy term and late-preterm Chinese infants.
Indexed as
Identifiers
20814696What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.