Evidence map›Paper›PMID 20814546›Full record

ReviewJournal of biomedicine & biotechnology2010

Tumor microenvironment and immune effects of antineoplastic therapy in lymphoproliferative syndromes.

Tomás Alvaro, Luis de la Cruz-Merino, Fernando Henao-Carrasco, José Luis Villar Rodríguez, David Vicente Baz, Manuel Codes Manuel de Villena, Mariano Provencio

Abstract readReview
In one paragraph

Review in Journal of biomedicine & biotechnology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tomás AlvaroPathology Department, Hospital de Tortosa Verge de la Cinta, 41300 Tortosa, Spain.
Luis de la Cruz-Merino
Fernando Henao-Carrasco
José Luis Villar Rodríguez
David Vicente Baz
Manuel Codes Manuel de Villena
Mariano Provencio

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphomas represent a wide group of heterogenic diseases with different biological and clinical behavior. The underlying microenvironment-specific composition seems to play an essential role in this scenario, harboring the ability to develop successful immune responses or, on the contrary, leading to immune evasion and even promotion of tumor growth. Depending on surrounding lymphoid infiltrates, lymphomas may have different prognosis. Moreover, recent evidences have emerged that confer a significant impact of main lymphoma's treatment over microenvironment, with clinical consequences. In this review, we summarize these concepts from a pathological and clinical perspective. Also, the state of the art of lymphoma's anti-idiotype vaccine development is revised, highlighting the situations where this strategy has proven to be successful and eventual clues to obtain better results in the future.

Indexed as

Tumor MicroenvironmentAnimalsAntineoplastic AgentsHumansLymphoproliferative DisordersAntineoplastic Agents

Identifiers

PMID20814546
PMCPMC2931385

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.