ArticleCell2010
Viable rat-mouse chimeras: where do we go from here?
Article in Cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- The beginning of becoming a human.Aging · 2024Review
- Expression dynamics and relations with nearby genes of rat transposable elements across 11 organs, 4 developmental stages and both sexes.BMC genomics · 2017Article
- Livestock models for exploiting the promise of pluripotent stem cells.ILAR journal · 2015Review
- Future of liver transplantation: non-human primates for patient-specific organs from induced pluripotent stem cells.World journal of gastroenterology · 2011Review
- Mouse chimeras as a system to investigate development, cell and tissue function, disease mechanisms and organ regeneration.Cell cycle (Georgetown, Tex.) · 2011Review
Corrections and comments
- Comment on
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In a tour-de-force study, Kobayashi et al. (2010) describe the first viable rat-mouse chimeras and demonstrate that rat induced pluripotent stem (iPS) cells can rescue organ deficiency in mice. Rat iPS cells formed a fully functional pancreas when injected into mouse blastocysts lacking the Pdx1 gene required for pancreas formation.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.