ReviewThe British journal of surgery2011
Intraoperative assessment of sentinel lymph nodes in breast cancer.
Review in The British journal of surgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 121 citations in OpenAlex.
- Prognostic significance of occult lymph node metastases in breast cancer: a meta-analysis.BMC cancer · 2021Pooled it
- An intra-operative RT-LAMP method allows rapid and reliable detection of sentinel lymph node metastasis in breast cancer patients.Virchows Archiv : an international journal of pathology · 2015Trial
- Sentinel Lymph Node Positivity and Utility of Frozen Section Diagnosis following Neoadjuvant Therapy in Patients with Clinically Node-Negative, Hormone Receptor-Positive, HER2-Negative Breast Cancer.Annals of surgical oncology · 2026Observational
- Fluorescence imaging of sentinel lymph nodes in breast cancer: a bibliometric analysis of global research trends (2000-2025).Gland surgery · 2026Article
- Virtual histology imaging of lymph nodesCancer biology & medicine · 2026Observational
- Article
- Comparative Analysis of Histomorphological Quality and Quantitative Cell Assessment in Formalin-Fixed Paraffin-Embedded and Fresh Frozen Porcine Skin Biopsies.Biomedicines · 2026Article
- Intraoperative evaluation of metastatic SLNs with NIRF imaging assisted by artificial intelligence in breast cancers.International journal of surgery (London, England) · 2026Observational
- Surgical landmarks for identification of the thoracodorsal pedicle during axillary dissection in carcinoma breast patients: a prospective observational study.BMC surgery · 2025Observational
- Article
- Should surgeons reconsider the role of intraoperative sentinel lymph node evaluation for premenopausal breast cancer patients in the era of RxPONDER?American journal of surgery · 2024Article
- Sentinel Lymph Node Biopsy in Prostate Cancer: An Overview of Diagnostic Performance, Oncological Outcomes, Safety, and Feasibility.Diagnostics (Basel, Switzerland) · 2023Review
- The Role of Surgical Axillary Staging Prior to Immediate Breast Reconstruction in the Era of De-Escalation of Axillary Management in Early Breast Cancer.Journal of personalized medicine · 2022Article
- Article
- Article
- Evaluation of Intraoperative Frozen Section Analysis with Final Histopathology Results for Sentinel Lymph Node Biopsy: Z0011 Criteria Eligible Versus Ineligible Breast Cancer Patients.Geburtshilfe und Frauenheilkunde · 2022Article
- Axillary Lymph Node Dissection Can Be Omitted in Breast Cancer Patients With Mastectomy and False-Negative Frozen Section in Sentinel Lymph Node Biopsy.Frontiers in oncology · 2022Article
- Novel Biomarkers Aim at Detecting Metastatic Sentinel Lymph Nodes in Breast CancerIranian biomedical journal · 2020Article
- Is the frozen section examination for sentinel lymph node necessary in early breast cancer patients?Annals of surgical treatment and research · 2019Article
- Nomogram to predict non-sentinel lymph node status using total tumor load determined by one-step nucleic acid amplification: first report from Thailand.Breast cancer (Tokyo, Japan) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundSentinel lymph node biopsy (SLNB) reduces the morbidity of axillary clearance and is the standard of care for patients with clinically node-negative breast cancer. The ability to analyse the sentinel node during surgery enables a decision to be made whether to proceed to full axillary clearance during primary surgery, thus avoiding a second procedure in node-positive patients.
methodsCurrent evidence for intraoperative sentinel node analysis following SLNB in breast cancer was reviewed and evaluated, based on articles obtained from a MEDLINE search using the terms 'sentinel node', 'intra-operative' and 'breast cancer'. RESULTS AND
conclusionCurrent methods for evaluating the sentinel node during surgery include cytological and histological techniques. Newer quantitative molecular assays have been the subject of much recent clinical research. Pathological techniques of intraoperative SLNB analysis such as touch imprint cytology and frozen section have a high specificity, but a lower and more variably reported sensitivity. Molecular techniques are potentially able to sample a greater proportion of the sentinel node, and could have higher sensitivity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.