ArticleCurrent protocols in microbiology2010
Cell-based hepatitis C virus infection fluorescence resonance energy transfer (FRET) assay for antiviral compound screening.
Article in Current protocols in microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 20 citations in OpenAlex.
- Modeling in vitro cell-to-cell spread of hepatitis C viral infection using an agent-based approach.bioRxiv : the preprint server for biology · 2026Article
- Immortalized hepatocyte-like cells: A competent hepatocyte model for studying clinical HCV isolate infection.PloS one · 2024Article
- Article
- HCV Spread Kinetics Reveal Varying Contributions of Transmission Modes to Infection Dynamics.Viruses · 2021Article
- Intracellular Hepatitis C Virus Modeling Predicts Infection Dynamics and Viral Protein Mechanisms.Journal of virology · 2018Article
- A robust model of natural hepatitis C infection using hepatocyte-like cells derived from human induced pluripotent stem cells as a long-term host.Virology journal · 2016Article
- Quantification of Hepatitis C Virus Cell-to-Cell Spread Using a Stochastic Modeling Approach.Journal of virology · 2015Article
- A novel method for the measurement of hepatitis C virus infectious titres using the IncuCyte ZOOM and its application to antiviral screening.Journal of virological methods · 2015Article
- Hepatitis C virus Cell-to-cell Spread Assay.Bio-protocol · 2014Article
- Determining the involvement and therapeutic implications of host cellular factors in hepatitis C virus cell-to-cell spread.Journal of virology · 2014Article
- Antioxidant and Anti-Hepatitis C Viral Activities of Commercial Milk Thistle Food Supplements.Antioxidants (Basel, Switzerland) · 2013Article
- Identification of hepatitis C virus inhibitors targeting different aspects of infection using a cell-based assay.Antimicrobial agents and chemotherapy · 2012Article
- Permissiveness of human hepatoma cell lines for HCV infection.Virology journal · 2012Article
- Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor.Nature medicine · 2012Article
- Hepatitis C Viral Kinetics in the Era of Direct Acting Antiviral Agents and IL28B.Current hepatitis reports · 2011Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Hepatitis C virus (HCV) affects an estimated 3% of the population and is a leading cause of chronic liver disease worldwide. Since HCV therapeutic and preventative options are limited, the development of new HCV antivirals has become a global health care concern. This has spurred the development of cell-based infectious HCV high-throughput screening assays to test the ability of compounds to inhibit HCV infection. This unit describes methods that may be used to assess the in vitro efficacy of HCV antivirals using a cell-based high-throughput fluorescence resonance energy transfer (FRET) HCV infection screening assay, which allows for the identification of inhibitors that target HCV at any step in the viral life cycle. Basic protocols are provided for compound screening during HCV infection and analysis of compound efficacy using an HCV FRET assay. Support protocols are provided for propagation of infectious HCV and measurement of viral infectivity.
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Registered trials
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