Evidence map›Paper›PMID 20812049›Full record

ReviewWiener medizinische Wochenschrift (1946)2010

[Adipokine update - new molecules, new functions].

Carmen Gelsinger, Alexander Tschoner, Susanne Kaser, Christoph F Ebenbichler

Abstract readReview
PubMed Publisher
In one paragraph

Review in Wiener medizinische Wochenschrift (1946), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Carmen GelsingerUniversitätsklinik für Innere Medizin I, Department Innere Medizin, Medizinische Universität Innsbruck, Innsbruck, Austria.
Alexander Tschoner
Susanne Kaser
Christoph F Ebenbichler

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of obesity is rising worldwide. Recent research findings show that adipose tissue is a highly active endocrine organ, which is involved in many physiological processes. These metabolic processes are influenced by products of the adipose tissue, so-called adipokines, which play a crucial role in the pathogenesis of the metabolic syndrome and cardiovascular disease. In addition, the two major fat depots - intraabdominal and subcutaneous - differ in their ability to secrete adipokines. In recent years the importance of the association between intraabdominal fat and the development of insulin resistance, diabetes mellitus type 2 and dyslipidemia was recognized. Therefore, accumulation of visceral adipose tissue contributes due to its ability to secrete a different pattern of adipokines to increased morbidity and mortality. This review aims to characterize novel, newly recognized adipokines and to discuss their roles in the pathogenesis of insulin resistance and atherosclerosis, as well as other metabolic complications.

Indexed as

AdipocytesAdipokinesAdiponectinAnimalsApelinAtherosclerosisBrainCardiovascular DiseasesChemokinesComplement Factor DCytokinesDiabetes Mellitus, Type 2Fatty Acid-Binding ProteinsFemaleGPI-Linked ProteinsHumansAdipokinesAdiponectinADIPOQ protein, humanApelinAPLN protein, humanCFD protein, humanChemokinesComplement Factor DCytokinesFABP4 protein, humanFatty Acid-Binding ProteinsGPI-Linked ProteinsIntercellular Signaling Peptides and ProteinsITLN1 protein, humanLectinsRARRES2 protein, humanRBP4 protein, humanReceptors, AdipokineResistinRetinol-Binding Proteins, PlasmaRETN protein, humanSERPINA12 protein, humanSerpins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.