ArticleGastroenterology research and practice2010
Toll-like receptors in hepatic ischemia/reperfusion and transplantation.
Article in Gastroenterology research and practice, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 37 citations in OpenAlex.
- iRhom2 regulates HMGB1 secretion to modulate inflammation and hepatocyte senescence in an in vitro model of ischemia-reperfusion injury.Cell death & disease · 2026Article
- Mechanistic insights into neutrophil involvement in liver transplant ischemia-reperfusion injury and rejection.Frontiers in immunology · 2026Review
- Thymoquinone-loaded self-nano-emulsifying drug delivery system against ischemia/reperfusion injury.Drug delivery and translational research · 2024Article
- Review
- Interleukin-27 in liver xenotransplantation: A rational target to mitigate ischemia reperfusion injury and increase xenograft survival.Transplantation reviews (Orlando, Fla.) · 2022Review
- Therapeutic Potential of Hemoglobin Derived from the Marine WormMarine drugs · 2021Review
- Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury.Cell death & disease · 2021Article
- Modulation of diabetes-related liver injury by the HMGB1/TLR4 inflammatory pathway.Journal of physiology and biochemistry · 2018Article
- mRNA Expression of Interferon Regulatory Factors during Acute Rejection of Liver Transplants in Patients with Autoimmune Hepatitis.International journal of organ transplantation medicine · 2018Article
- Peroxiredoxin-6 Negatively Regulates Bactericidal Activity and NF-κB Activity by Interrupting TRAF6-ECSIT Complex.Frontiers in cellular and infection microbiology · 2017Article
- Toll-like receptors in pathophysiology of liver diseases.World journal of hepatology · 2016Review
- Superoxide induces Neutrophil Extracellular Trap Formation in a TLR-4 and NOX-dependent mechanism.Molecular medicine (Cambridge, Mass.) · 2016Article
- Toll-like receptor 4 (TLR4) antagonist eritoran tetrasodium attenuates liver ischemia and reperfusion injury through inhibition of high-mobility group box protein B1 (HMGB1) signaling.Molecular medicine (Cambridge, Mass.) · 2015Article
- Article
- The effects of preoperative immunosuppressive therapy on ischemia and reperfusion (I/R) injury in healthy rats.International urology and nephrology · 2014Article
- Histones activate the NLRP3 inflammasome in Kupffer cells during sterile inflammatory liver injury.Journal of immunology (Baltimore, Md. : 1950) · 2013Article
- Signaling of high mobility group box 1 (HMGB1) through toll-like receptor 4 in macrophages requires CD14.Molecular medicine (Cambridge, Mass.) · 2013Article
- Ethyl pyruvate ameliorates hepatic ischemia-reperfusion injury by inhibiting intrinsic pathway of apoptosis and autophagy.Mediators of inflammation · 2013Article
- Calcium/calmodulin-dependent protein kinase IV limits organ damage in hepatic ischemia-reperfusion injury through induction of autophagy.American journal of physiology. Gastrointestinal and liver physiology · 2012Article
- MyD88 mediated inflammatory signaling leads to CaMKII oxidation, cardiac hypertrophy and death after myocardial infarction.Journal of molecular and cellular cardiology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The family of Toll-like receptors (TLRs) function as pattern-recognition receptors (PRRs) that respond to a myriad of highly conserved ligands. These substrates include pathogen-associated molecular patterns (PAMPs) for the recognition of invading pathogens, as well as damage-associated molecular patterns (DAMPs) for the recognition of endogenous tissue injury. While the functions of TLRs are diverse, they have received much attention for their roles in ischemia/reperfusion (I/R) injury of the liver and other organs. The TLRs play central roles in sensing tissue damage and activating the innate immune system following I/R. Engagement of TLRs by endogenous DAMPs activates proinflammatory signaling pathways leading to the production of cytokines, chemokines and further release of endogenous danger signals. This paper focuses on the most recent findings regarding TLR family members in hepatic I/R injury and transplantation.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.