Evidence map›Paper›PMID 20811486›Full record

ArticleInternational journal of cell biology2010

Review on Trypanosoma cruzi: Host Cell Interaction.

Wanderley de Souza, Tecia Maria Ulisses de Carvalho, Emile Santos Barrias

Open access · goldAbstract read
In one paragraph

Article in International journal of cell biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 232 citations in OpenAlex.

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  7. Infectivity of Aflagellar Epimastigotes ofJournal of parasitology research · 2025
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  9. RNA and protein immunization withFrontiers in cellular and infection microbiology · 2025
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  10. Apoptosis: A Key Process ThatJournal of parasitology research · 2025
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  12. Review
  13. Trypanosomiasis: An emerging disease in Alpine swift (International journal for parasitology. Parasites and wildlife · 2024
    Article
  14. Parasite Burden ofMicroorganisms · 2024
    Article
  15. New insights intoFrontiers in immunology · 2024
    Review
  16. Review
  17. IncreasedLife (Basel, Switzerland) · 2023
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  18. Murine colon organoids as a novel model to studyFrontiers in cellular and infection microbiology · 2023
    Article
  19. Article
  20. Article

51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Wanderley de SouzaLaboratório de Ultraestrutura Celular Hertha Meyer, CCS, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Bloco G, Ilha do Fundão, RJ 21941-902, Brazil.
Tecia Maria Ulisses de Carvalho
Emile Santos Barrias
Instituto Nacional de Metrologia, Qualidade e Tecnologia · BRNational Institute of Science and Technology for Structural Biology and Bioimaging · BRUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trypanosoma cruzi, the causative agent of Chagas' disease, which affects a large number of individuals in Central and South America, is transmitted to vertebrate hosts by blood-sucking insects. This protozoan is an obligate intracellular parasite. The infective forms of the parasite are metacyclic and bloodstream trypomastigote and amastigote. Metacyclic trypomastigotes are released with the feces of the insect while amastigotes and bloodstream trypomastigotes are released from the infected host cells of the vertebrate host after a complex intracellular life cycle. The recognition between parasite and mammalian host cell involves numerous molecules present in both cell types. Here, we present a brief review of the interaction between Trypanosoma cruzi and its host cells, mainly emphasizing the mechanisms and molecules that participate in the T. cruzi invasion process of the mammalian cells.

Identifiers

PMID20811486
PMCPMC2926652
OpenAlexW1973926329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.