Evidence map›Paper›PMID 20811286›Full record

ArticleEpidemiology (Cambridge, Mass.)2010

Prenatal exposure to fine particulate matter and birth weight: variations by particulate constituents and sources.

Michelle L Bell, Kathleen Belanger, Keita Ebisu, Janneane F Gent, Hyung Joo Lee, Petros Koutrakis, Brian P Leaderer

Open access · greenAbstract read
In one paragraph

Article in Epidemiology (Cambridge, Mass.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 5 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 5 syntheses or guidelines pooled it, 246 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Maternal fine particulate matter (PMEnvironmental science and pollution research international · 2019
    Pooled it
  4. Maternal exposure to fine particulate matter (PM2.5) and pregnancy outcomes: a meta-analysis.Environmental science and pollution research international · 2015
    Pooled it
  5. Pooled it
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. The MAK collection for occupational health and safety · 2025
    Article
  12. Review
  13. Sources of personal PMJournal of exposure science & environmental epidemiology · 2024
    Article
  14. Article
  15. Article
  16. Association Between Individual Air Pollution (PMJournal of Korean medical science · 2024
    Observational
  17. Article
  18. Review
  19. Article
  20. Article

40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Michelle L BellYale University, School of Forestry and Environmental Studies, New Haven, CT 06511, USA. michelle.bell@yale.edu
Kathleen Belanger
Keita Ebisu
Janneane F Gent
Hyung Joo Lee
Petros Koutrakis
Brian P Leaderer
Yale University · US

Funding

Genetic &Environmental Risk Factors in Asthma SeverityR01ES011013 · NIEHS · YALE UNIVERSITY · PI LEADERER, BRIAN P · 2001 to 2010
$4.9M
Effect of Air Pollution and Traffic on Birth OutcomesR01ES016317 · NIEHS · YALE UNIVERSITY · PI BELANGER, KATHLEEN, BELL, MICHELLE L · 2008 to 2012
$2.9M
NIEHS NIH HHS ES11013NIEHS NIH HHS R01 ES011013NIEHS NIH HHS R01 ES016317NIEHS NIH HHS R01ES016317
6 · The paper itself

Abstract

backgroundExposure to fine particles (PM2.5) during pregnancy has been linked to lower birth weight; however, the chemical composition of PM2.5 varies widely. The health effects of PM2.5 constituents are unknown.

methodsWe investigated whether PM2.5 mass, constituents, and sources are associated with birth weight for term births. PM2.5 filters collected in 3 Connecticut counties and 1 Massachusetts county from August 2000 through February 2004 were analyzed for more than 50 elements. Source apportionment was used to estimate daily contributions of PM2.5 sources, including traffic, road dust/crustal, oil combustion, salt, and regional (sulfur) sources. Gestational and trimester exposure to PM2.5 mass, constituents, and source contributions were examined in relation to birth weight and risk of small-at-term birth (term birth <2500 g) for 76,788 infants.

resultsRoad dust and related constituents such as silicon and aluminum were associated with lower birth weight, as were the motor-vehicle-related species such as elemental carbon and zinc, and the oil-combustion-associated elements vanadium and nickel. An interquartile range increase in exposure was associated with low birthweight for zinc (12% increase in risk), elemental carbon (13%), silicon (10%), aluminum (11%), vanadium (8%), and nickel (11%). Analysis by trimester showed effects of third-trimester exposure to elemental carbon, nickel, vanadium, and oil-combustion PM2.5.

conclusionsExposures of pregnant women to higher levels of certain PM2.5 chemical constituents originating from specific sources are associated with lower birth weight.

Indexed as

Infant, Low Birth WeightMaternal ExposureAdultAir PollutantsBirth WeightConnecticutFemaleHumansInfant, NewbornMaleMassachusettsModels, TheoreticalParticle SizePregnancyAir Pollutants

Identifiers

PMID20811286
PMCPMC3055585
OpenAlexW2044492613

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.