ArticleThe American journal of tropical medicine and hygiene2010
Effects of annual mass treatment with ivermectin for onchocerciasis on the prevalence of intestinal helminths.
Article in The American journal of tropical medicine and hygiene, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Association between footwear use and neglected tropical diseases: a systematic review and meta-analysis.PLoS neglected tropical diseases · 2014Pooled it
- Zoonotic Risk of Intestinal Parasites in Ghana's Protected Areas: A Nexus for Human-Nonhuman Primates-Dog Interactions.Journal of parasitology research · 2026Article
- Ivermectin Inhibits Zika Virus Replication in Vitro But Does Not Prevent Zika Virus Infection in Rhesus Macaques (Macaca mulatta).The American journal of tropical medicine and hygiene · 2025Article
- Persistent transmission of soil-transmitted helminths despite 16 years of uninterrupted Mebendazole- and ivermectin-based preventive chemotherapy in the Lomie Health District (East Region, Cameroon): The emergency of complementary control strategies.PLoS neglected tropical diseases · 2024Article
- Effectiveness of one and two doses of ivermectin mass drug administration in reducing the prevalence and intensity of soil-transmitted helminth (STH) infections in Western Province, Solomon Islands: a cluster-randomised, before-after analysis.The Lancet regional health. Western Pacific · 2024Article
- Article
- Serious limitations of the current strategy to control Soil-Transmitted Helminths and added value of Ivermectin/Albendazole mass administration: A population-based observational study in Cameroon.PLoS neglected tropical diseases · 2020Observational
- Octopamine signaling in the metazoan pathogenDisease models & mechanisms · 2018Article
- Assessment of the burden of soil-transmitted helminthiasis after five years of mass drug administration for Onchocerciasis and Lymphatic filariasis in Kebbi State, Nigeria.Parasite epidemiology and control · 2017Article
- A Knowledge, Attitudes and Practices Survey Conducted Three Years after Halting Ivermectin Mass Treatment for Onchocerciasis in Guatemala.PLoS neglected tropical diseases · 2016Article
- Mass Administration of Ivermectin for the Elimination of Onchocerciasis Significantly Reduced and Maintained Low the Prevalence of Strongyloides stercoralis in Esmeraldas, Ecuador.PLoS neglected tropical diseases · 2015Article
- Should the Goal for the Treatment of Soil Transmitted Helminth (STH) Infections Be Changed from Morbidity Control in Children to Community-Wide Transmission Elimination?PLoS neglected tropical diseases · 2015Article
- The Contributions of Onchocerciasis Control and Elimination Programs toward the Achievement of the Millennium Development Goals.PLoS neglected tropical diseases · 2015Review
- African Program for Onchocerciasis Control 1995-2010: Impact of Annual Ivermectin Mass Treatment on Off-Target Infectious Diseases.PLoS neglected tropical diseases · 2015Article
- Rationale for the coadministration of albendazole and ivermectin to humans for malaria parasite transmission control.The American journal of tropical medicine and hygiene · 2014Article
- Community-wide distribution of long-lasting insecticidal nets can halt transmission of lymphatic filariasis in southeastern Nigeria.The American journal of tropical medicine and hygiene · 2013Article
- Ivermectin to reduce malaria transmission: a research agenda for a promising new tool for elimination.Malaria journal · 2013Article
- A qualitative study exploring barriers related to use of footwear in rural highland ethiopia: implications for neglected tropical disease control.PLoS neglected tropical diseases · 2013Article
- The Binding Interactions of the Macrolide Endectocide Ivermectin with the Antibiotics Ampicillin, Chloramphenicol and Tetracycline HCL.Indian journal of pharmaceutical sciences · 2012Article
- Endectocides for malaria control.Trends in parasitology · 2011Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
We evaluated the effect of annual ivermectin (IV) distribution for onchocerciasis on the prevalence of soil transmitted helminth (STH) infections in school-aged (SAC) and preschool-aged (PAC) children by comparing children in villages that had received treatment for 13 years to those from socioeconomically similar villages in untreated areas. We enrolled 1,031 SAC and 211 PAC for Kato Katz examinations. Treated areas had a lower prevalence of Ascaris (SAC: 3% versus 12%, P < 0.0001; PAC: 3% versus 10%, P < 0.051) and Trichuris (SAC: 6% versus 10%, P = 0.012; PAC: 1% versus 8%, P = 0.019), but not hookworm (SAC: 38% versus 42%, P = 0.20; PAC: 21% versus 27%, P = 0.30). The prevalence of Ascaris or Trichuris in treated areas was below the WHO threshold for mass antihelminthic treatment (MDA), but not for hookworm. We conclude that benzimidazole MDA in IV treatment areas is indicated to effectively control hookworm.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.