ArticleBiology letters2011
Phenoloxidase but not lytic activity reflects resistance against Pasteuria ramosa in Daphnia magna.
Article in Biology letters, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 26 citations in OpenAlex.
- Responses to a warming world: Integrating life history, immune investment, and pathogen resistance in a model insect species.Ecology and evolution · 2017Article
- Condition-Dependent Trade-Off Between Weapon Size and Immunity in Males of the European Earwig.Scientific reports · 2017Article
- Article
- Article
- Insect immunity: oral exposure to a bacterial pathogen elicits free radical response and protects from a recurring infection.Frontiers in zoology · 2014Article
- Gene expression profiling of three different stressors in the water flea Daphnia magna.Ecotoxicology (London, England) · 2013Article
- Disentangling the influence of parasite genotype, host genotype and maternal environment on different stages of bacterial infection in Daphnia magna.Proceedings. Biological sciences · 2012Article
- Evolutionary ecotoxicology of pesticide resistance: a case study in Daphnia.Ecotoxicology (London, England) · 2011Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The field of ecological immunology strongly relies on indicators of immunocompetence. Two major indicators in invertebrates, the activity of phenoloxidase (PO) and lytic activity have recently been questioned in studies showing that, across a natural range of baseline levels, these indicators did not predict resistance against a manipulated challenge with natural parasites. We confirmed this finding by showing that baseline levels of PO and lytic activity in the host Daphnia magna were not related to spore load of the parasite Pasteuria ramosa. Yet, PO levels in infected hosts did predict spore load, indicating PO activity can be useful as an indicator of immunocompetence in this model parasite-host system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.