Evidence map›Paper›PMID 20809957›Full record

SynthesisSubstance abuse treatment, prevention, and policy2010

Maternal substance use and integrated treatment programs for women with substance abuse issues and their children: a meta-analysis.

Karen Milligan, Alison Niccols, Wendy Sword, Lehana Thabane, Joanna Henderson, Ainsley Smith, Jennifer Liu

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Substance abuse treatment, prevention, and policy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04251208 (MOms in REcovery), which is not on this map. Cited by 30 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 6 pooled it
4.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04251208 completednot on this mapstarted 2019, after this paper: background citation

MOms in REcovery (MORE): Defining Optimal Care for Pregnant Women and Infants

TypeobservationalSponsorTrustees of Dartmouth CollegeRan2019 to 2024Enrolled444ConditionsOpioid-Related Disorders, NAS, Substance Use DisordersArmsObservational Study
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 6 syntheses or guidelines pooled it, 87 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Family systems therapy for substance-using mothers and their 8- to 16-year-old children.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2016
    Trial
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Intergenerational continuity in alcohol misuse: Maternal alcohol use disorder and the sequelae of maternal and family functioning.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2019
    Article
  17. Article
  18. Article
  19. Neonatal abstinence syndrome.Nature reviews. Disease primers · 2018
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Karen MilliganIntegra, 25 Imperial Street, Toronto, ON, M5P 1B9, Canada. kmilligan@integra.on.ca
Alison Niccols
Wendy Sword
Lehana Thabane
Joanna Henderson
Ainsley Smith
Jennifer Liu
McMaster University · CAHamilton Health Sciences · CAIntegral Consulting (United States) · USUniversity of Toronto · CA

Funding

Canadian Institutes of Health Research 162119
6 · The paper itself

Abstract

backgroundThe rate of women with substance abuse issues is increasing. Women present with a unique constellation of risk factors and presenting needs, which may include specific needs in their role as mothers. Numerous integrated programs (those with substance use treatment and pregnancy, parenting, or child services) have been developed to specifically meet the needs of pregnant and parenting women with substance abuse issues. This synthesis and meta-analysis reviews research in this important and growing area of treatment.

methodsWe searched PsycINFO, MedLine, PubMed, Web of Science, EMBASE, Proquest Dissertations, Sociological Abstracts, and CINAHL and compiled a database of 21 studies (2 randomized trials, 9 quasi-experimental studies, 10 cohort studies) of integrated programs published between 1990 and 2007 with outcome data on maternal substance use. Data were summarized and where possible, meta-analyses were performed, using standardized mean differences (d) effect size estimates.

resultsIn the two studies comparing integrated programs to no treatment, effect sizes for urine toxicology and percent using substances significantly favored integrated programs and ranged from 0.18 to 1.41. Studies examining changes in maternal substance use from beginning to end of treatment were statistically significant and medium sized. More specifically, in the five studies measuring severity of drug and alcohol use, the average effect sizes were 0.64 and 0.40, respectively. In the four cohort studies of days of use, the average effect size was 0.52. Of studies comparing integrated to non-integrated programs, four studies assessed urine toxicology and two assessed self-reported abstinence. Overall effect sizes for each measure were not statistically significant (d = -0.09 and 0.22, respectively).

conclusionsFindings suggest that integrated programs are effective in reducing maternal substance use. However, integrated programs were not significantly more effective than non-integrated programs. Policy implications are discussed with specific attention to the need for funding of high quality randomized control trials and improved reporting practices.

Indexed as

Mother-Child RelationsFemaleHumansSubstance-Related Disorders

Identifiers

PMID20809957
PMCPMC2942813
OpenAlexW2142178715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.