ReviewClinical research in cardiology : official journal of the German Cardiac Society2011
Heart rate reduction in cardiovascular disease and therapy.
Review in Clinical research in cardiology : official journal of the German Cardiac Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 102 citations in OpenAlex.
- Effect of ivabradine on cardiovascular outcomes in patients with stable angina: meta-analysis of randomized clinical trials.BMC cardiovascular disorders · 2017Pooled it
- Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomization Meta-Analysis in the CARTA Consortium.Circulation. Cardiovascular genetics · 2015Pooled it
- Ivabradine treatment in a chronic heart failure patient cohort: symptom reduction and improvement in quality of life in clinical practice.Advances in therapy · 2014Trial
- Heart rate is associated with increased risk of major cardiovascular events, cardiovascular and all-cause death in patients with stable chronic cardiovascular disease: an analysis of ONTARGET/TRANSCEND.Clinical research in cardiology : official journal of the German Cardiac Society · 2014Trial
- Heart rate at baseline influences the effect of ivabradine on cardiovascular outcomes in chronic heart failure: analysis from the SHIFT study.Clinical research in cardiology : official journal of the German Cardiac Society · 2013Trial
- Ivabradine in combination with beta-blocker improves symptoms and quality of life in patients with stable angina pectoris: results from the ADDITIONS study.Clinical research in cardiology : official journal of the German Cardiac Society · 2012Trial
- Heart Rate, Electrocardiographic Subclinical Myocardial Injury, and Long-Term Mortality.Journal of clinical medicine · 2026Article
- Assessment of the impact of resting heart rate on the risk of major adverse cardiovascular events after ischemic stroke: a retrospective observational study.BMC neurology · 2024Observational
- Evaluating the applicability of ivabradine in acute heart failure.Clinical cardiology · 2024Article
- Association between Obstructive Sleep Apnea and Heart Failure in Adults-A Systematic Review.Journal of clinical medicine · 2023Review
- Impact of heart rate, aortic compliance and stroke volume on the aortic regurgitation fraction studied in an ex vivo pig model.Open heart · 2023Article
- Optimal Heart Rate Control Improves Long-Term Prognosis of Decompensated Heart Failure with Reduced Ejection Fraction.Medicina (Kaunas, Lithuania) · 2023Article
- Relationships between sympathetic markers and heart rate thresholds for cardiovascular risk in chronic heart failure.Clinical research in cardiology : official journal of the German Cardiac Society · 2023Article
- Resting heart rate and risk of left and right heart failure in 0.5 million Chinese adults.Open heart · 2022Article
- Association of pulse rate with outcomes in heart failure with reduced ejection fraction: a retrospective cohort study.BMC cardiovascular disorders · 2020Observational
- The Association of Extreme Tachycardia and Sustained Return of Spontaneous Circulation after Nontraumatic Out-of-Hospital Cardiac Arrest.Emergency medicine international · 2020Article
- Physical activity may compensate for prolonged TV time regarding pulse rate-a cross-sectional study.Upsala journal of medical sciences · 2018Article
- Beta blockers and chronic heart failure patients: prognostic impact of a dose targeted beta blocker therapy vs. heart rate targeted strategy.Clinical research in cardiology : official journal of the German Cardiac Society · 2018Article
- Novel drugs for heart rate control in heart failure.Heart failure reviews · 2018Review
- Predictors of Post-discharge Mortality Among Patients Hospitalized for Acute Heart Failure.Cardiac failure review · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 6 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heart rate influences myocardial oxygen demand, coronary blood flow, and myocardial function. Clinical and experimental studies support an association between elevated resting heart rate and a broad range of maladaptive effects on the function and structure of the cardiovascular system. Heart rate has been shown to be an important predictor of mortality in cardiovascular disorders such as coronary artery disease, myocardial infarction, and chronic heart failure. This review summarizes the specific influence of heart rate on vascular morphology and function as well as on myocardial lesions leading from early impact on vascular homeostasis to myocardial hemodynamics in chronic heart failure. Heart rate can be easily determined during physical examination of the patient and therefore allows a simple hint on prognosis and efficiency of therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.