Evidence map›Paper›PMID 20809276›Full record

Trial reportPharmacy world & science : PWS2010

The effect of a clinical pharmacist discharge service on medication discrepancies in patients with heart failure.

Rixt Nynke Eggink, Albert W Lenderink, Jos W M G Widdershoven, Patricia M L A van den Bemt

Registry-linked trialOpen access · hybridAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Pharmacy world & science : PWS, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02752997 (Reducing 30-day Readmissions in Patients With Heart Failure Through Pharmacist Discharge Medication Services), which is not on this map. Cited by 48 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 9 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02752997 nacompletednot on this mapstarted 2015, after this paper: background citation

Reducing 30-day Readmissions in Patients With Heart Failure Through Pharmacist Discharge Medication Services

TypeinterventionalSponsorMayo ClinicRan2015 to 2016Enrolled24ConditionsHeart Failure, Patient ReadmissionArmsPharmacist discharge medication services
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 9 syntheses or guidelines pooled it, 115 citations in OpenAlex.

  1. Pooled it
  2. Discharge planning from hospital.The Cochrane database of systematic reviews · 2022
    Pooled it
  3. Pooled it
  4. Impact of medication reconciliation for improving transitions of care.The Cochrane database of systematic reviews · 2018
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Discharge planning from hospital.The Cochrane database of systematic reviews · 2016
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rixt Nynke EgginkDepartment of Clinical Pharmacy, TweeSteden Hospital and St. Elisabeth Hospital, PO Box 90107, 5000 LA, Tilburg, The Netherlands. r.n.eggink@antonius-sneek.nl
Albert W Lenderink
Jos W M G Widdershoven
Patricia M L A van den Bemt
Elisabeth-TweeSteden Ziekenhuis · NLErasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHeart failure patients are regularly admitted to hospital and frequently use multiple medication. Besides intentional changes in pharmacotherapy, unintentional changes may occur during hospitalisation. The aim of this study was to investigate the effect of a clinical pharmacist discharge service on medication discrepancies and prescription errors in patients with heart failure.

settingA general teaching hospital in Tilburg, the Netherlands.

methodAn open randomized intervention study was performed comparing an intervention group, with a control group receiving regular care by doctors and nurses. The clinical pharmacist discharge service consisted of review of discharge medication, communicating prescribing errors with the cardiologist, giving patients information, preparation of a written overview of the discharge medication and communication to both the community pharmacist and the general practitioner about this medication. Within 6 weeks after discharge all patients were routinely scheduled to visit the outpatient clinic and medication discrepancies were measured.

main outcome measureThe primary endpoint was the frequency of prescription errors in the discharge medication and medication discrepancies after discharge combined.

resultsForty-four patients were included in the control group and 41 in the intervention group. Sixty-eight percent of patients in the control group had at least one discrepancy or prescription error against 39% in the intervention group (RR 0.57 (95% CI 0.37-0.88)). The percentage of medications with a discrepancy or prescription error in the control group was 14.6% and in the intervention group it was 6.1% (RR 0.42 (95% CI 0.27-0.66)).

conclusionThis clinical pharmacist discharge service significantly reduces the risk of discrepancies and prescription errors in medication of patients with heart failure in the 1st month after discharge.

Indexed as

Patient DischargePharmacistsProfessional RoleAgedAged, 80 and overFemaleHeart FailureHumansMaleMedication ErrorsMiddle AgedNetherlandsPharmacy Service, HospitalRisk Factors

Identifiers

PMID20809276
PMCPMC2993887
OpenAlexW2149879094

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.