ReviewPediatric surgery international2010
Clinical risk factors for gastroschisis and omphalocele in humans: a review of the literature.
Review in Pediatric surgery international, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 4 syntheses or guidelines pooled it, 153 citations in OpenAlex.
- Medication use during pregnancy and the risk of gastroschisis: a systematic review and meta-analysis of observational studies.Orphanet journal of rare diseases · 2024Pooled it
- Effect of paternal age on offspring birth defects: a systematic review and meta-analysis.Aging · 2020Pooled it
- Gastroschisis: antenatal sonographic predictors of adverse neonatal outcome.Journal of pregnancy · 2014Pooled it
- Parental risk factors and anorectal malformations: systematic review and meta-analysis.Orphanet journal of rare diseases · 2011Pooled it
- The course and surgical management of a complex, giant omphalocele in a term neonate.Proceedings (Baylor University. Medical Center) · 2026Article
- Maternal Risk Factors for Omphalocele.Fetal diagnosis and therapy · 2026Article
- Omphalocele with a patent vitelline duct: intraoperative identification of an uncommon presentation.Maternal health, neonatology and perinatology · 2026Article
- Prenatal and Postnatal Determinants of Outcome in Neonates with Omphalocele: A 25-Year Single-Center Cohort Study.Journal of clinical medicine · 2026Article
- Seasonal and geographic patterns of gastroschisis in Canada: protective effect of periconceptional sunlight exposure.Frontiers in endocrinology · 2026Article
- Omphalocele and Associated Anomalies: Exploring Pulmonary Development and Genetic Correlations-A Literature Review.Diagnostics (Basel, Switzerland) · 2025Review
- Haploinsufficiency ofFrontiers in cell and developmental biology · 2025Article
- Omphalocele prevalence and co-occurring malformations: a nationwide register-based study of Danish live births in 1997-2021.Pediatric surgery international · 2024Article
- Perinatal outcomes of antenatally diagnosed omphalocele and gastroschisis: a survey from a university hospital.Journal of the Turkish German Gynecological Association · 2024Article
- Anatomic parameters of omphaloceles and their association with anatomic, genetic, or syndromic malformations: a retrospective study.Pediatric surgery international · 2024Article
- Article
- Ruptured giant omphalocele with congenital short small intestine: a case report.Frontiers in nutrition · 2024Article
- Enhancing Omphalocele Care: Navigating Complications and Innovative Treatment Approaches.Cureus · 2023Review
- The Alberta Congenital Anomalies Surveillance System: a 40-year review with prevalence and trends for selected congenital anomalies, 1997-2019.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2023Article
- Bovine omphalocele: errors in embryonic development, veterinarian importance, and the way forward.Veterinary research communications · 2022Review
- Current Challenges in the Treatment of the Omphalocele-Experience of a Tertiary Center from Romania.Journal of clinical medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastroschisis and omphalocele are usually considered together since they are both congenital abdominal wall defects, and yet their anatomy, embryogenesis, and clinical presentation and problems are quite different. In addition, it appears that the risk factors for their occurrence differ. Etiologic factors contributing to the development of these defects are unknown. To investigate this we have reviewed reports of risk factors for each anomaly and report them here. We conducted a literature search using PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) for risk factors implicated in the development of gastroschisis and omphalocele. The data reviewed here from clinical studies in the literature, closely parallels the data in animal studies which we reported earlier. There is little evidence for a genetic cause in the development of gastroschisis and much evidence supporting the possibility that environmental teratogens are important contributors to the development of this defect. On the other hand, in the case of omphalocele, there was little evidence for environmental factors and substantial data indicating that genetic or familial factors may play an important role.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.