ArticlePloS one2010
Analysis of vascular development in the hydra sterol biosynthetic mutants of Arabidopsis.
Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 34 citations in OpenAlex.
- Farnesol and geranylgeraniol in plant reproduction: insights from Arabidopsis and beyond.Journal of experimental botany · 2026Review
- TOR Signaling as a Central Integrator of Embryogenic Reprogramming During 2,4-D-Induced Somatic Embryogenesis.International journal of molecular sciences · 2026Review
- Brassinosteroid biosynthesis and signaling: Conserved and diversified functions of core genes across multiple plant species.Plant communications · 2024Review
- Molecular Insights into the Role of Sterols in Microtuber Development of PotatoPlants (Basel, Switzerland) · 2024Article
- Arabidopsis 3β-Hydroxysteroid Dehydrogenases/C4-Decarboxylases Are Essential for the Pollen and Embryonic Development.International journal of molecular sciences · 2023Article
- Membrane Sterol Composition inInternational journal of molecular sciences · 2021Article
- Epidermal expression of a sterol biosynthesis gene regulates root growth by a non-cell-autonomous mechanism inDevelopment (Cambridge, England) · 2018Article
- Suppressing a Putative Sterol Carrier Gene Reduces Plasmodesmal Permeability and Activates Sucrose Transporter Genes during Cotton Fiber Elongation.The Plant cell · 2017Article
- Sterol Methyl Oxidases Affect Embryo Development via Auxin-Associated Mechanisms.Plant physiology · 2016Article
- The VASCULATURE COMPLEXITY AND CONNECTIVITY gene encodes a plant-specific protein required for embryo provasculature development.Plant physiology · 2014Article
- Callose homeostasis at plasmodesmata: molecular regulators and developmental relevance.Frontiers in plant science · 2014Article
- Arabidopsis ERG28 tethers the sterol C4-demethylation complex to prevent accumulation of a biosynthetic intermediate that interferes with polar auxin transport.The Plant cell · 2013Article
- Boosting crop yields with plant steroids.The Plant cell · 2012Review
- Genome-wide transcriptome analysis of gametophyte development in Physcomitrella patens.BMC plant biology · 2011Article
- Brassinosteroids.The arabidopsis book · 2011Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe control of vascular tissue development in plants is influenced by diverse hormonal signals, but their interactions during this process are not well understood. Wild-type sterol profiles are essential for growth, tissue patterning and signalling processes in plant development, and are required for regulated vascular patterning. METHODOLOGY/PRINCIPAL
findingsHere we investigate the roles of sterols in vascular tissue development, through an analysis of the Arabidopsis mutants hydra1 and fackel/hydra2, which are defective in the enzymes sterol isomerase and sterol C-14 reductase respectively. We show that defective vascular patterning in the shoot is associated with ectopic cell divisions. Expression of the auxin-regulated AtHB8 homeobox gene is disrupted in mutant embryos and seedlings, associated with variably incomplete vascular strand formation and duplication of the longitudinal axis. Misexpression of the auxin reporter proIAA2ratioGUS and mislocalization of PIN proteins occurs in the mutants. Introduction of the ethylene-insensitive ein2 mutation partially rescues defective cell division, localization of PIN proteins, and vascular strand development.
conclusionsThe results support a model in which sterols are required for correct auxin and ethylene crosstalk to regulate PIN localization, auxin distribution and AtHB8 expression, necessary for correct vascular development.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.