ArticleCurrent genomics2010
Simulation of genes and genomes forward in time.
Article in Current genomics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Article
- SLiM 5: Eco-evolutionary Simulations Across Multiple Chromosomes and Full Genomes.Molecular biology and evolution · 2026Article
- Article
- Parameter Scaling in Population Genetics Simulations may Introduce Unintended Background Selection: Considerations for Scaled Simulation Design.Genome biology and evolution · 2025Article
- Article
- AdmixSim 2: a forward-time simulator for modeling complex population admixture.BMC bioinformatics · 2021Article
- Evolutionary Modeling in SLiM 3 for Beginners.Molecular biology and evolution · 2019Article
- Genetic signatures of small effective population sizes and demographic declines in an endangered rattlesnake,Evolutionary applications · 2019Article
- SLiM 3: Forward Genetic Simulations Beyond the Wright-Fisher Model.Molecular biology and evolution · 2019Article
- Accelerating Wright-Fisher Forward Simulations on the Graphics Processing Unit.G3 (Bethesda, Md.) · 2017Article
- Intricacies in arrangement of SNP haplotypes suggest "Great Admixture" that created modern humans.BMC genomics · 2017Article
- Approaching Long Genomic Regions and Large Recombination Rates with msParSm as an Alternative to MaCS.Evolutionary bioinformatics online · 2016Review
- Clotho: addressing the scalability of forward time population genetic simulation.BMC bioinformatics · 2015Article
- Genetic data simulators and their applications: an overview.Genetic epidemiology · 2015Article
- Alignathon: a competitive assessment of whole-genome alignment methods.Genome research · 2014Article
- Spatial and temporal simulation of human evolution. Methods, frameworks and applications.Current genomics · 2014Article
- SMARTPOP: inferring the impact of social dynamics on genetic diversity through high speed simulations.BMC bioinformatics · 2014Article
- Genome evolution by matrix algorithms: cellular automata approach to population genetics.Genome biology and evolution · 2014Article
- SLiM: simulating evolution with selection and linkage.Genetics · 2013Article
- Rapid forward-in-time simulation at the chromosome and genome level.BMC bioinformatics · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The importance of simulation software in current and future evolutionary and genomic studies is just confirmed by the recent publication of several new simulation tools. The forward-in-time simulation strategy has, therefore, re-emerged as a complement of coalescent simulation. Additionally, more efficient coalescent algorithms, the same as new ideas about the combined use of backward and forward strategies have recently appeared. In the present work, a previous review is updated to include some new forward simulation tools. When simulating at the genome-scale the conflict between efficiency (i.e. execution speed and memory usage) and flexibility (i.e. complex modeling capabilities) emerges. This is the pivot around which simulation of evolutionary processes should improve. In addition, some effort should be made to consider the process of developing simulation tools from the point of view of the software engineering theory. Finally, some new ideas and technologies as general purpose graphic processing units are commented.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.