Evidence map›Paper›PMID 20808092›Full record

Trial reportThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2010

Home-delivered problem adaptation therapy (PATH) for depressed, cognitively impaired, disabled elders: A preliminary study.

Dimitris N Kiosses, Patricia A Arean, Linda Teri, George S Alexopoulos

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 11 pooled it
7.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 11 syntheses or guidelines pooled it, 91 citations in OpenAlex.

  1. Pooled it
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  5. Interventions for preventing abuse in the elderly.The Cochrane database of systematic reviews · 2016
    Pooled it
  6. Pooled it
  7. Pooled it
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  9. Citalopram versus other anti-depressive agents for depression.The Cochrane database of systematic reviews · 2012
    Pooled it
  10. Counselling for mental health and psychosocial problems in primary care.The Cochrane database of systematic reviews · 2011
    Pooled it
  11. Pooled it
  12. Measuring Participant Effort in a Depression Prevention Trial: Who Engages in Problem-Solving Therapy?The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2017
    Trial
  13. Improving health-related quality of life in older African American and non-Latino White patients.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2015
    Trial
  14. Trial
  15. Trial
  16. The peaceful mind program: a pilot test of a cognitive-behavioral therapy-based intervention for anxious patients with dementia.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2013
    Trial
  17. Article
  18. Psychotherapy for older adults with depression: a narrative review.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dimitris N KiossesDepartment of Psychiatry, Weill-Cornell Institute of Geriatric Psychiatry, Weill Medical College of Cornell University, New York, NY, USA. dkiosses@med.cornell.edu
Patricia A Arean
Linda Teri
George S Alexopoulos
Cornell University · USUniversity of California, San Francisco · US

Funding

Research Methods CoreP30MH085943 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALEXOPOULOS, GEORGE S · 2009 to 2013
$9.2M
Treating Depressed, Cognitively Impaired EldersK23MH074659 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI KIOSSES, DIMITRIS N · 2006 to 2010
$802k
NIMH NIH HHS K23 MH074659NIMH NIH HHS P30 MH085943
6 · The paper itself

Abstract

objectivesThis preliminary study examines the efficacy of 12-week home-delivered problem adaptation therapy (PATH) versus home-delivered supportive therapy (ST) in reducing depression and disability in 30 depressed, cognitively impaired, disabled older adults.

designA 12-week randomized clinical trial. Research assistants were unaware of the participants' randomization status. Assessments were conducted at baseline, 6 weeks, and 12 weeks.

settingWeill-Cornell Advanced Center for Interventions and Services Research.

participantsThirty elders with major depression, cognitive impairment, and disability were recruited through advertisement and the Home-Delivered Meals Program of the Westchester County Department of Senior Programs and Services.

interventionPATH is a home-delivered intervention designed to reduce depression and disability in depressed, cognitively impaired, disabled elders. PATH is based on problem-solving therapy and integrates environmental adaptation and caregiver participation. PATH is consistent with Lawton's ecologic model of adaptive functioning in aging. MEASUREMENTS: Depression and disability were measured with Hamilton Depression Rating Scale-24 items and Sheehan Disability Scale, respectively. Client Satisfaction Questionnaire was used to assess patient satisfaction with treatment.

resultsMixed-effects model analyses revealed that PATH was more efficacious than ST in reducing depression and disability at 12 weeks. Participants in both treatment groups were satisfied with treatment.

conclusionsThis preliminary study suggests that PATH is well accepted and efficacious in depressed elders with major depression, cognitive impairment, and disability. Because this population may not adequately respond to antidepressant medication treatment, PATH may provide relief to many patients who would otherwise remain depressed and continue to suffer.

Indexed as

Adaptation, PsychologicalAgedAged, 80 and overCognition DisordersFemaleGeriatric AssessmentHome Care ServicesHumansMajor Depressive DisorderMalePatient Acceptance of Health CarePersons with DisabilitiesPsychotherapy

Identifiers

PMID20808092
PMCPMC2962702
OpenAlexW2074097311

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.