ArticleAddictive behaviors2010
A quantitative analysis of subjective, cognitive, and physiological manifestations of the acute tobacco abstinence syndrome.
Article in Addictive behaviors, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
62 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Global prevalence of smoking among individuals with obsessive-compulsive disorder and symptoms: a systematic review and meta-analysis.Health psychology review · 2023Pooled it
- Possible New Symptoms of Tobacco Withdrawal III: Reduced Positive Affect-A Review and Meta-analysis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021Pooled it
- Cigarette smoking and depression comorbidity: systematic review and proposed theoretical model.Addiction (Abingdon, England) · 2017Pooled it
- Behavioural tasks sensitive to acute abstinence and predictive of smoking cessation success: a systematic review and meta-analysis.Addiction (Abingdon, England) · 2016Pooled it
- Pain characteristics and nicotine deprivation as predictors of performance during a laboratory paradigm of smoking cessation.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020Trial
- Phase IIb Trial of an α7 Nicotinic Receptor Partial Agonist With and Without Nicotine Patch for Withdrawal-Associated Cognitive Deficits and Tobacco Abstinence.Journal of clinical psychopharmacology · 2018Trial
- Ovarian Hormones and Transdermal Nicotine Administration Independently and Synergistically Suppress Tobacco Withdrawal Symptoms and Smoking Reinstatement in the Human Laboratory.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018Trial
- Mechanisms underlying mindfulness-based addiction treatment versus cognitive behavioral therapy and usual care for smoking cessation.Journal of consulting and clinical psychology · 2017Trial
- Effect of attentional retraining on cognition, craving, and smoking in African American smokers.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2017Trial
- What a difference a day makes: differences in initial abstinence response during a smoking cessation attempt.Addiction (Abingdon, England) · 2017Trial
- Pharmacological, sensorimotor, and expectancy effects on tobacco withdrawal: a preliminary study.Human psychopharmacology · 2015Trial
- Anhedonia as a component of the tobacco withdrawal syndrome.Journal of abnormal psychology · 2015Trial
- The effects of acute abstinence from smoking and performance-based rewards on performance monitoring.Psychopharmacology · 2013Trial
- Positive and negative affect as predictors of urge to smoke: temporal factors and mediational pathways.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2013Trial
- Tobacco withdrawal components and their relations with cessation success.Psychopharmacology · 2011Trial
- Tobacco withdrawal system recovery time assessed during smoking satiety predicts smoking behavior change among individuals who smoke cigarettes daily.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026Article
- Aerobic exercise for substance use disorders: therapeutic effects and underlying mechanisms.Frontiers in medicine · 2026Review
- Tobacco deprivation impairs metacognitive accuracy and cognitive flexibility.Psychopharmacology · 2025Article
- Effects of intranasal oxytocin on cigarette withdrawal and smoking in the laboratory: Differences by sex and social functioning traits.Experimental and clinical psychopharmacology · 2024Article
- Effects of mint, menthol, and tobacco-flavored e-cigarettes on tobacco withdrawal symptoms in adults who smoke menthol cigarettes: A laboratory pilot study.Drug and alcohol dependence · 2024Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
rationalePrevious studies have documented the existence of signs and symptoms of the acute tobacco abstinence syndrome; however, less attention has been paid to quantifying the magnitude of these effects.
objectiveThe present study quantified the relative magnitude of subjective, cognitive, and physiological manifestations of acute tobacco abstinence.
methodSmokers (N=203, ≥ 15 cig/day) attended two counterbalanced laboratory sessions, one following 12-h of abstinence and the other following ad-lib smoking. At both sessions, they completed an extensive battery of self-report measures (withdrawal, affect, hunger, craving, subjective attentional bias towards smoking cues), physiological assessments (heart rate, blood pressure, brain EEG), and cognitive performance tasks (psychomotor processing, sustained attention, objective attentional bias).
resultsAbstinence effects were largest for craving, subjective attentional bias, negative affect, overall withdrawal severity, concentration difficulty, hunger, and heart rate. Effects were moderate for positive affect and EEG power. Effects were small, but reliable, for psychomotor speed, sustained attention, and somatic symptoms. Effects on performance-based indices of attentional bias towards smoking-related cues were small and reliable for some indices but not others. Effects were small and inconsistent for blood pressure and EEG frequency. Variation in internal consistency accounted for 33% of the variation in abstinence effect sizes across measures.
conclusionsThere was a wide range of effect sizes both across and within domains, indicating that the acute tobacco abstinence syndrome is not a monotonic phenomenon. These findings may be indicative of the relative magnitudes of signs and symptoms that the average smoker may exhibit during acute abstinence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.