ArticleWorld journal of gastroenterology2010
Age-dependent eradication of Helicobacter pylori in Japanese patients.
Article in World journal of gastroenterology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- LOW-NICKEL DIET AS A STRATEGY IN THE TREATMENT OF HELICOBACTER PYLORI INFECTION.Arquivos de gastroenterologia · 2025Trial
- Efficacy of Omeprazole, Tetracycline, and 4 Times Daily Dosing of Amoxicillin in Helicobacter pylori Eradication in Limited Resource Area in Bhutan: A Prospective Randomized Trial (BHUTAN Study).Asian Pacific journal of cancer prevention : APJCP · 2020Trial
- Evaluation of Helicobacter Pylori eradication in pediatric patients by triple therapy plus lactoferrin and probiotics compared to triple therapy alone.Italian journal of pediatrics · 2012Trial
- Two-week triple therapy has a higher Helicobacter pylori eradication rate than 1-week therapy: A single-center randomized study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology AssociationTrial
- Factors associated with heterochronic gastric cancer development post-endoscopic mucosal dissection in early gastric cancer patients.World journal of gastrointestinal oncology · 2023Article
- Factors Affecting the Intraluminal Therapy forMicroorganisms · 2022Article
- Eradication of Helicobacter pylori may improve dyspepsia in the elderly for the long term.BMC gastroenterology · 2021Article
- Clinical factors associated with initial Helicobacter pylori eradication therapy: a retrospective study in China.Scientific reports · 2020Article
- Clinical background factors affecting outcomes ofJournal of general and family medicine · 2019Article
- Vonoprazan-Based Third-Line Therapy Has a Higher Eradication Rate against Sitafloxacin-Resistant Helicobacter pylori.Cancers · 2019Article
- Effects of patient age and choice of antisecretory agent on success of eradication therapy forJournal of clinical biochemistry and nutrition · 2017Article
- Efficacy of 7-Day and 14-Day Triple Therapy Regimens for the Eradication of Helicobacter pylori: A Comparative Study in a Cohort of Romanian Patients.Gastroenterology research and practice · 2016Article
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8 authors.
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Abstract
aimTo determine the general risk factors affecting the failure rate of first-line eradication therapy in Japanese patients with Helicobacter pylori (H. pylori) infection.
methodsThe present study enrolled 253 patients who had an H. pylori infection, underwent gastro-endoscopy, and were treated with H. pylori eradication therapy. Eradication therapy consisted of 30 mg lansoprazole plus 750 mg amoxicillin and 400 mg clarithromycin twice daily for 7 d. All of the patients underwent a 13C urea breath test at least 1 mo after the completion of eradication therapy. The current study investigated the independent factors associated with successful H. pylori eradication using a multiple logistic regression analysis.
resultsThe overall success rate in the patients was 85.8%. Among the general factors examined in the multivariate analyses, only having an age less than 50 years was found to be significantly associated with a poor response to H. pylori eradication. Moreover, side effects were the only clinical factors in the patients who were under 50 years of age that significantly influenced the poor response to H. pylori eradication.
conclusionH. pylori-positive elderly patients should undergo eradication therapy. In addition, it is necessary to improve H. pylori eradication therapy in younger patients.
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