Evidence map›Paper›PMID 20806154›Full record

ArticleEndoscopy2010

Interobserver reliability in the endoscopic diagnosis and grading of Barrett's esophagus: an Asian multinational study.

Y C Lee, M B Cook, S Bhatia, W H Chow, E M El-Omar, H Goto, J T Lin, Y Q Li, P L Rhee, P Sharma and 5 more

Abstract readMulticenter Study
In one paragraph

Article in Endoscopy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Prevalence of Barrett's Esophagus in Asian Countries: A Systematic Review and Meta-analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2015
    Pooled it
  2. Article
  3. How to Define the Gastroesophageal Junction.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Development of a prediction score for Barrett's esophagus in Japanese health checkup settings.Esophagus : official journal of the Japan Esophageal Society · 2024
    Article
  8. Article
  9. Review
  10. Review
  11. Observational
  12. Article
  13. Article
  14. Indian consensus on gastroesophageal reflux disease in adults: A position statement of the Indian Society of Gastroenterology.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2019
    Article
  15. Review
  16. Article
  17. Risk stratifying the screening of Barrett's esophagus: An Asian perspective.JGH open : an open access journal of gastroenterology and hepatology · 2017
    Article
  18. Review
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Y C LeeDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
M B Cook
S Bhatia
W H Chow
E M El-Omar
H Goto
J T Lin
Y Q Li
P L Rhee
P Sharma
J J Sung
J Y Wong
J C Wu
K Y Ho
Asian Barrett's Consortium

Funding

Cancer Risk in Human PopulationsZIACP010136 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI PURDUE, MARK · 2009 to 2025
$36.7M
Intramural NIH HHS ZIA CP010136
6 · The paper itself

Abstract

BACKGROUND AND STUDY

aimThe establishment of precise and valid diagnostic criteria is important for any disease. We determined the interobserver reliability in the endoscopic diagnosis and grading of Barrett's esophagus. PATIENTS AND

methodsVideo clips of endoscopy in 21 patients with/without Barrett's esophagus were used for training (n = 3) and for diagnosis/grading (n = 18) of Barrett's esophagus by endoscopists from seven hospitals in Asia. Barrett's esophagus was graded using the Prague C & M Criteria whereby the circumferential extent of the Barrett's segment (C value), maximum extent of Barrett's segment (M value), location of the gastroesophageal junction, and location of the diaphragmatic hiatus were scored. The intraclass correlation coefficients (ICC) were calculated as a measure of interobserver reliability.

resultsA total of 34 endoscopists participated. ICC values for the scores of the C value, M value, location of the gastroesophageal junction, and location of the diaphragmatic hiatus were: 0.92 (95 % confidence interval [CI] 0.88 - 0.97), 0.94 (95 %CI 0.90 - 0.98), 0.86 (95 %CI 0.78 - 0.94), and 0.81 (95 %CI 0.71 - 0.92), respectively, indicating excellent interobserver agreement. The differences in region/country, endoscopists' experience, case volume of participating centers, or primary practice type had no significant effect on the reliability. The ICC values for recognition of Barrett's esophagus of > or = 1 cm were 0.90 (95 %CI 0.80 - 1.00) and 0.92 (95 %CI 0.87 - 0.98) for the C and M values, respectively, whereas the corresponding ICC values for Barrett's segment of < 1 cm were 0.18 (95 %CI 0.03 - 0.32) and 0.21 (95 %CI 0.00 - 0.51), respectively.

conclusionsDespite the uncommon occurrence of Barrett's esophagus in Asia, our endoscopists exhibited excellent agreement in the endoscopic diagnosis and grading of Barrett's esophagus using the Prague C & M Criteria. However, in view of the low interobserver reliability in recognizing Barrett's segments of < 1 cm, future studies in Asia should take this into account when selecting the study population.

Indexed as

AsiaBarrett EsophagusClinical CompetenceEsophagoscopyHumansObserver VariationReproducibility of Results

Identifiers

PMID20806154
PMCPMC3000217

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.