ArticlePloS one2010
Parasite replication and the evolutionary epidemiology of parasite virulence.
Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Double trouble: trypanosomatids with two hosts have lower infection prevalence than single host trypanosomatids.Evolution, medicine, and public health · 2023Article
- Competition, virulence, host body mass and the diversification of macro-parasites.Journal of the Royal Society, Interface · 2014Article
- Altruism and the evolution of resource generalism and specialism.Ecology and evolution · 2012Article
- To be or not to be solitary: Phytophthora infestans' dilemma for optimizing its reproductive fitness in multiple infections.PloS one · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Parasite virulence evolution is shaped by both within-host and population-level processes yet the link between these differing scales of infection is often neglected. Population structure and heterogeneity in both parasites and hosts will affect how hosts are exploited by pathogens and the intensity of infection. Here, it is shown how the degree of relatedness among parasites together with epidemiological parameters such as pathogen yield and longevity influence the evolution of virulence. Furthermore, the role of kin competition and the degree of cheating within highly structured parasite populations also influences parasite fitness and infectivity patterns. Understanding how the effects of within-host processes scale up to affect the epidemiology has importance for understanding host-pathogen interactions.
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Registered trials
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