Evidence map›Paper›PMID 20805792›Full record

ArticleNature methods2010

Exhaustive benchmarking of the yeast two-hybrid system.

Yu-Chi Chen, Seesandra Venkatappa Rajagopala, Thorsten Stellberger, Peter Uetz

Abstract readCommentLetter
In one paragraph

Article in Nature methods, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Molecular characterization of Satsuma mandarin (Plant biotechnology (Tokyo, Japan) · 2023
    Article
  7. What Has Genomics Taught An Evolutionary Biologist?Genomics, proteomics & bioinformatics · 2023
    Review
  8. Yeast Two-Hybrid System for Mapping Novel Dengue Protein Interactions.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Protein-protein interactions of human viruses.Seminars in cell & developmental biology · 2020
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Making the Right Choice: Critical Parameters of the Y2H Systems.Methods in molecular biology (Clifton, N.J.) · 2018
    Article
  19. Article
  20. High-throughput characterization of protein-protein interactions by reprogramming yeast mating.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Yu-Chi Chen
Seesandra Venkatappa Rajagopala
Thorsten Stellberger
Peter Uetz

Funding

A Protein-Protein Interaction Map of Escherichia coliR01GM079710 · NIGMS · J. CRAIG VENTER INSTITUTE, INC. · PI RAJAGOPALA, SEESANDRA VENKATAPPA · 2008 to 2011
$2.5M
NIGMS NIH HHS R01 GM079710NIGMS NIH HHS R01GM79710
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Two-Hybrid System TechniquesHumansProtein BindingProtein Interaction MappingRecombinant ProteinsReference StandardsReproducibility of ResultsRecombinant Proteins

Identifiers

PMID20805792
PMCPMC10332476

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.