ReviewMayo Clinic proceedings2010
Ethical decision making with end-of-life care: palliative sedation and withholding or withdrawing life-sustaining treatments.
Review in Mayo Clinic proceedings, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Attitudes of undergraduate medical students towards end-of-life decisions: a systematic review of influencing factors.BMC medical education · 2025Pooled it
- The Czech Bill on palliative care, end-of-life decision-making, and euthanasia in light of Belgian legislative experience.BMC medical ethics · 2026Article
- Connect or detach: A transformative experience for medical students in end-of-life care.Medical education · 2025Article
- Continuous Sedation in Palliative Care in Portugal: A Prospective Multicentric Study.Journal of palliative care · 2025Article
- Navigating end-of-life decision-making in nursing: a systematic review of ethical challenges and palliative care practices.BMC nursing · 2024Article
- Expanded terminal sedation in end-of-life care.Journal of medical ethics · 2023Article
- Palliative Care Across the Life Span for Children With Heart Disease: A Scientific Statement From the American Heart Association.Circulation. Cardiovascular quality and outcomes · 2023Review
- Dexmedetomidine and Propofol at End of Life in Pediatric Oncology: Trends in Palliative Sedation Therapy.Journal of palliative medicine · 2023Article
- Review
- Ethical and Legal Concerns Associated With Withdrawing Mechanical Circulatory Support: A U.S. Perspective.Frontiers in cardiovascular medicine · 2022Review
- Ageism, human rights and ethical aspects of end-of-life care for older people with serious mental illness.Frontiers in psychiatry · 2022Article
- Palliative Care in Pediatric Pulmonology.Children (Basel, Switzerland) · 2021Review
- Prevalence of palliative sedation in the State of São Paulo: an emerging medical demand.Einstein (Sao Paulo, Brazil) · 2020Observational
- Palliative sedation and medical assistance in dying: Distinctly different or simply semantics?Nursing inquiry · 2020Article
- Continuous palliative sedation for patients with advanced cancer at a tertiary care cancer center.BMC palliative care · 2018Article
- International Association for Hospice and Palliative Care Position Statement: Euthanasia and Physician-Assisted Suicide.Journal of palliative medicine · 2017Article
- US Physicians' Opinions about Distinctions between Withdrawing and Withholding Life-Sustaining Treatment.Journal of religion and health · 2016Article
- Religious, Ethical and Legal Considerations in End-of-Life Issues: Fundamental Requisites for Medical Decision Making.Journal of religion and health · 2016Review
- When Suicide Is Not Suicide: Self-induced Morbidity and Mortality in the General Hospital.Rambam Maimonides medical journal · 2015Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Palliative sedation (PS) is the use of medications to induce decreased or absent awareness in order to relieve otherwise intractable suffering at the end of life. Although uncommon, some patients undergoing aggressive symptom control measures still have severe suffering from underlying disease or therapy-related adverse effects. In these circumstances, use of PS is considered. Although the goal is to provide relief in an ethically acceptable way to the patient, family, and health care team, health care professionals often voice concerns whether such treatment is necessary or whether such treatment equates to physician-assisted suicide or euthanasia. In this review, we frame clinical scenarios in which PS may be considered, summarize the ethical underpinnings of the practice, and further differentiate PS from other forms of end-of-life care, including withholding and/or withdrawing life-sustaining therapy and physician-assisted suicide and euthanasia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.