ArticleProceedings of the National Academy of Sciences of the United States of America2010
A transmembrane formin nucleates subapical actin assembly and controls tip-focused growth in pollen tubes.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
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Who cites it
78 citing papers in PubMed, 143 citations in OpenAlex.
- Article
- Cytoskeletal control of development and environmental adaptation in plants.Science China. Life sciences · 2026Review
- Article
- Heat-stable protein PGSL1 enhances pollen germination and tube growth at high temperature.Nature communications · 2025Article
- A land plant-specific VPS13 mediates polarized vesicle trafficking in germinating pollen.The New phytologist · 2025Article
- Article
- AtFH5 recruits and transports the arabinogalactan protein AGP23 to maintain the tip growth of pollen tube.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Transmembrane formins as active cargoes of membrane trafficking.Journal of experimental botany · 2024Review
- From gametes to zygote: Mechanistic advances and emerging possibilities in plant reproduction.Plant physiology · 2024Review
- Genome-Wide Studies ofPlants (Basel, Switzerland) · 2024Article
- Differential sensitivity of ADF isovariants to a pH gradient promotes pollen tube growth.The Journal of cell biology · 2023Article
- Exploring the Role of the Plant Actin Cytoskeleton: From Signaling to Cellular Functions.International journal of molecular sciences · 2023Review
- Activation of actin-depolymerizing factor by CDPK16-mediated phosphorylation promotes actin turnover in Arabidopsis pollen tubes.PLoS biology · 2023Article
- Actin-bundling protein fimbrin regulates pathogenicity via organizing F-actin dynamics during appressorium development in Colletotrichum gloeosporioides.Molecular plant pathology · 2022Article
- O-glycosylation of the extracellular domain of pollen class I formins modulates their plasma membrane mobility.Journal of experimental botany · 2022Article
- Cell biology of primary cell wall synthesis in plants.The Plant cell · 2022Review
- A rich and bountiful harvest: Key discoveries in plant cell biology.The Plant cell · 2022Review
- Article
- Analysis of formin functions during cytokinesis using specific inhibitor SMIFH2.Plant physiology · 2021Article
- The quest for the central players governing pollen tube growth and guidance.Plant physiology · 2021Review
18 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pollen tubes are highly polarized plant cells specialized in delivering sperm for fertilization. Pollen tube growth is rapid, occurs exclusively at the tip, and can reach distances thousands of times the diameter of the pollen grain without cell division, thus representing an excellent model system for studying asymmetric cell growth. In flowering plants, pollen tube growth is dependent on the actin cytoskeleton, which supports an efficient vesicle trafficking system to deliver membrane and cell-wall materials to the tube tip. A highly dynamic subapical actin structure and an apical vesicular zone are known to be critical for the tip-growth process. How this apical organization is maintained, how the subapical actin structure is assembled, and direct evidence for its functional coupling with tip growth remain to be established. Here, we show that a tip-located, cell membrane-anchored actin-nucleating protein, the Arabidopsis formin homology5 (FH5), stimulates actin assembly from the subapical membrane, provides actin filaments for vesicular trafficking to the apical dome, and mediates assembly of the subapical actin structure. Moreover, FH5-expressing pollen tubes provided a unique opportunity to demonstrate that assembly of the subapical actin structure is concomitant with the acquisition of rapid tip growth, providing further support for their functional coupling. Together, our results show that FH5 plays a pivotal role in establishing the subapical actin and apical vesicular organization critical for tip-focused growth in pollen tubes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.