ArticleDiabetes care2010
Differences in maternal circulating fatty acid composition and dietary fat intake in women with gestational diabetes mellitus or mild gestational hyperglycemia.
Article in Diabetes care, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 4 syntheses or guidelines pooled it, 139 citations in OpenAlex.
- The Use of Omics in Untangling the Effect of Lifestyle Factors in Pregnancy and Gestational Diabetes: A Systematic Review.Diabetes/metabolism research and reviews · 2025Pooled it
- Association of circulating omega 3, 6 and 9 fatty acids with gestational diabetes mellitus: a systematic review.BMC endocrine disorders · 2021Pooled it
- Mild Gestational Diabetes and Adverse Pregnancy Outcome: A Systemic Review and Meta-Analysis.Frontiers in medicine · 2021Pooled it
- Pooled it
- The impact of fish oil and/or probiotics on serum fatty acids and the interaction with low-grade inflammation in pregnant women with overweight and obesity: secondary analysis of a randomised controlled trial.The British journal of nutrition · 2024Trial
- Physical activity and individual plasma phospholipid SFAs in pregnancy: a longitudinal study in a multiracial/multiethnic cohort in the United States.The American journal of clinical nutrition · 2022Trial
- Maternal obesity, fish intake, and recurrent spontaneous preterm birth.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2019Trial
- The Effect of Omega-3 Docosahexaenoic Acid Supplementation on Gestational Length: Randomized Trial of Supplementation Compared to Nutrition Education for Increasing n-3 Intake from Foods.BioMed research international · 2015Trial
- Placental transport dysfunction in omega-3 and omega-6 fatty acid in patients with gestational diabetes mellitus.Annals of medicine · 2026Article
- Prognostic biomarkers of future diabetes in South Asian women diagnosed with gestational diabetes: a prospective cohort study.BMC endocrine disorders · 2026Article
- Dietary Intake and Eating Behavior During Pregnancy by Pre-Pregnancy Nutritional Status.Life (Basel, Switzerland) · 2026Article
- High Serum Polyunsaturated Fatty Acids for the Increased Risk of Gestational Diabetes Mellitus Through LPC Pathways: A Prospective Nested Case-Control Study in China.Journal of diabetes research · 2026Article
- Non-Traditional Lipid Parameters and Risk of Adverse Pregnancy Outcomes in Gestational Diabetes Mellitus: Mediation by Maternal Metabolites.Journal of diabetes · 2025Observational
- Medical Nutrition Therapy for Women with Gestational Diabetes: Current Practice and Future Perspectives.Nutrients · 2025Review
- Article
- The Camden Study-A Pregnancy Cohort Study of Pregnancy Complications and Birth Outcomes in Camden, New Jersey, USA.Nutrients · 2024Article
- First-trimester metabolic profiling of gestational diabetes mellitus: insights into early-onset and late-onset cases compared with healthy controls.Frontiers in molecular biosciences · 2024Article
- An Integrated Multi-OMICS Approach Highlights Elevated Non-Esterified Fatty Acids Impact BeWo Trophoblast Metabolism and Lipid Processing.Metabolites · 2023Article
- Article
- Exploring preconception signatures of metabolites in mothers with gestational diabetes mellitus using a non-targeted approach.BMC medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveWe investigated the relationship between maternal circulating fatty acids (FAs) and dietary FA intake in pregnant women with gestational diabetes mellitus (GDM; n = 49), women with hyperglycemia less severe than GDM (impaired glucose challenge test [GCT] non-GDM; n = 80), and normal control subjects (n = 98). RESEARCH DESIGN AND
methodsA case-control design was nested within a prospective cohort of healthy pregnant women. Fasting concentrations of serum total FAs (enzymatic assay) and FA composition (gas chromatography-mass spectrometry) were determined at entry and the third trimester. Dietary fat intake data were obtained from 24-h recalls.
resultsThere was a graded increase among groups (control subjects, impaired GCT non-GDM, and GDM) during the third trimester for total FAs and individual FAs, including myristic, palmitic, palmitoleic, oleic, linoleic, linolenic, arachidonic, eicosapentaenoic, and docosahexaenoic acids (P for trend <0.03 to P < 0.001). Similar relationships were observed at entry in total FAs and for four FAs (myristic, palmitic, palmitoleic, and eicosapentaenoic acids). Women with impaired GCT non-GDM with BMI >or=25 kg/m(2) had the highest levels of FAs at entry, whereas women with GDM with BMI >or=25 kg/m(2) had the highest levels during the third trimester, and all grouped FAs were significantly different from lean women with impaired GCT non-GDM or control subjects (P < 0.05). Dietary intake of polyunsaturated FAs was decreased, but saturated FAs were increased in GDM compared with impaired GCT non-GDM or control subjects (P < 0.05).
conclusionsAbnormalities in fat metabolism are present in both GDM and impaired GCT non-GDM women. Reducing pregravid weight and altering diet might prevent the associated elevation of circulating FAs.
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Registered trials
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